111619-05-7Relevant articles and documents
Synthesis of 5-deazaflavin adenine dinucleotide (5-dFAD) using a modified triester approach
Smit, P.,Stork, G. A.,van der Plas, H. C.,den Hartog, J. A. J.,van der Marel, G. A.,van Boom, J. H.
, p. 538 - 543 (2007/10/02)
Starting from D-ribose and 3,4-xylidine, a fifteen-step synthesis is described for the preparation of 5-dFAD (18).The synthesis involves as key intermediates, 5-deazariboflavin (8), its 2',3',4'-tris-O-(tetrahydropyranyl) derivative (12) and 2',3',4'-tris-O-(tetrahydropyranyl)-5'-O-(morpholinophosphonyl)-5-deazaribolavin (15).
