111748-83-5

Basic information

• Product Name: 2(3H)-Furanone, 5-cyclohexyldihydro-4-methyl-, cis-
• CAS NO: 111748-83-5
• Molecular Formula: C11H18O2
• Molecular Weight: 182.263
• Mol File: 111748-83-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(3H)-Furanone, 5-cyclohexyldihydro-4-methyl-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, 5-cyclohexyldihydro-4-methyl-, cis-(111748-83-5)
• EPA Substance Registry System: 2(3H)-Furanone, 5-cyclohexyldihydro-4-methyl-, cis-(111748-83-5)

Safety Data

• Hazardous Substances Data: 111748-83-5(Hazardous Substances Data)

Upstream product

• 2043-61-0 cyclohexanecarbaldehyde 
• 119924-84-4 4-cyclohexyl-3-methyl-4-oxobutanoic acid methyl ester 
• 17264-02-7 cyclohexylpropyl alcohol 
• 1123-86-0 cyclohexyl ethyl ketone 
• 354762-23-5 5-cyclohexyl-4-methyl-tetrahydro-furan-2-ol 
• 623-43-8 crotonic acid methyl ester 
• 133101-43-6 γ-cyclohexyl-β-methyl-γ-oxobutanoic acid 

Relevant articles and documents

Reactivity of α-(benzoyloxy)crotylstannane with aldehydes in liquid phase and on solid support. Synthesis of substituted lactones

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Stereoselective Reduction of γ-Oxobutanoic Acids Using DIBAL-H and ZnCl2

A variety of γ-aromatic γ-ketobutanoic acids can be reduced selectively, under optimized conditions, by the use of DIBAL-H and ZnCl2 to provide the (RS,SR)-γ-aryl-γ-hydroxy-β-methylbutanoic acids.Further evidence has been gathered to support the hypothesis that the reaction proceeds by formation of a seven-membered ring complex with the aluminium or zinc atom bridging the ketone and carboxyl groups which preceeds the reduction step and that this templated reduction accounts for observed high diastereoselectivity.Also we have shown that some γ-aryl-γ-butyrolactones can be easily transformed via an oxidative cleavage of the aromatic ring to provide selective synthesis of either cis- or trans-tetrahydro-3-methyl-5-oxo-2-furancarboxylic acid derivatives.