111751-83-8

Basic information

• Product Name: 3-(4'-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone
• Synonyms: 3-(4'-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone
• CAS NO: 111751-83-8
• Molecular Weight: 297.313
• Mol File: 111751-83-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4'-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4'-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone(111751-83-8)
• EPA Substance Registry System: 3-(4'-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone(111751-83-8)

Safety Data

• Hazardous Substances Data: 111751-83-8(Hazardous Substances Data)

Upstream product

• 111751-80-5 2-(4'-benzyloxyphenyl)-3-(pyrrol-1-yl)propionic acid 
• 111751-82-7 2-(4'-acetoxyphenyl)-3-(pyrrol-1-yl)propionic acid 
• 111751-72-5 methyl 2-(4'-benzyloxyphenyl)propenoate 
• 111751-81-6 2-(4'-hydroxyphenyl)-3-(pyrrol-1-yl)propionic acid 
• 186581-53-3 diazomethane 

Downstream Products

• 111752-02-4 6-(4'-acetoxyphenyl)-1,2,3,5,6,7,8,8a-octahydro-7-methylindolizin-7-yl acetate 
• 111751-99-6 6-(4'-acetoxyphenyl)-2,3,5,6,8,8a-hexahydro-7(1H)-indolizinone 
• 26294-41-7 4-[7-methyl-1,2,3,5,8,8a-hexahydroindolizin-6-yl]phenol 
• 111751-87-2 6-(4'-acetoxyphenyl)-5,6-dihydro-7(8H)-indolizinone 

Relevant articles and documents

Intramolecular Carbenoid Reactions of Pyrrole Derivatives. A Total Synthesis of (+/-)-Ipalbidine

A mew method for alkaloid synthesis is described.The rhodium(II)-acetate-catalyzed decomposition of 3-(4-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone (5d) gave 6-(4-acetoxyphenyl)-5,6-dihydro-7(8H)-indolizinone (6d) in 82percent yield via an intramolecular carbenoid reaction.The latter compound was converted in four steps in 13percent overall yield to (+/-)-ipalbidine (1b).