111771-16-5

Basic information

• Product Name: Oxazole, 2-(2-fluoro-6-iodophenyl)-4,5-dihydro-4,4-dimethyl-
• CAS NO: 111771-16-5
• Molecular Formula: C11H11FINO
• Molecular Weight: 319.117
• Mol File: 111771-16-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxazole, 2-(2-fluoro-6-iodophenyl)-4,5-dihydro-4,4-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 2-(2-fluoro-6-iodophenyl)-4,5-dihydro-4,4-dimethyl-(111771-16-5)
• EPA Substance Registry System: Oxazole, 2-(2-fluoro-6-iodophenyl)-4,5-dihydro-4,4-dimethyl-(111771-16-5)

Safety Data

• Hazardous Substances Data: 111771-16-5(Hazardous Substances Data)

Upstream product

• 111771-14-3 N-(2-methyl-3-hydroxypropyl)-2-flouro-6-iodobenzamide 
• 111771-08-5 2-fluoro-6-iodobenzoic acid 
• 111771-12-1 2-fluoro-6-iodobenzoyl chloride 
• 66464-20-8 2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 1478-33-7 6-fluoro-2-<(5,6,7,8-tetrahydro-1-naphthalenyl)methyl>benzoic acid 

Relevant articles and documents

Directed functionalization of halophenyl-2-oxazolines with TMPMgCl?LiCl

A variety of difunctionalized aryl-2-oxazolines were prepared from the reaction of halophenyl-2-oxazolines and TMPMgCl?LiCl to give an organomagnesium reagent, which was then treated with various electrophiles. The metalation step takes place under mild conditions, and this process al-lows for the isolation of the desired products in good yields. No isomeric or other benzyne-derived products were detected. The influence of the halogen substituents on the acidity of the aromatic hydrogen atoms was evaluated by using density functional theory (DFT) calculations.