111787-88-3

Basic information

• Product Name: 5-(4-FLUOROPHENYL)-2-METHYL-3-FUROIC ACID
• Synonyms: 5-(4-FLUOROPHENYL)-2-METHYL-3-FUROIC ACID;5-(4-Fluoro-phenyl)-2-methyl-furan-3-carboxylic acid
• CAS NO: 111787-88-3
• Molecular Formula: C₁₂H₉FO₃
• Molecular Weight: 220.2
• Mol File: 111787-88-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 354.1°Cat760mmHg
• Flash Point: 167.9°C
• Appearance: /
• Density: 1.291g/cm³
• Vapor Pressure: 1.26E-05mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: 5-(4-FLUOROPHENYL)-2-METHYL-3-FUROIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-FLUOROPHENYL)-2-METHYL-3-FUROIC ACID(111787-88-3)
• EPA Substance Registry System: 5-(4-FLUOROPHENYL)-2-METHYL-3-FUROIC ACID(111787-88-3)

Safety Data

• Hazardous Substances Data: 111787-88-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H9FO3/c1-7-10(12(14)15)6-11(16-7)8-2-4-9(13)5-3-8/h2-6H,1H3,(H,14,15)

Upstream product

• 111787-83-8 ethyl 5-(4-fluorophenyl)-2-methylfuran-3-carboxylate 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 36967-50-7 ethyl 2-acetyl-4-(4-fluorophenyl)-4-oxobutanoate 
• 444914-29-8 methyl 5-(4-fluorophenyl)-2-methylfuran-3-carboxylate 

Relevant articles and documents

FURAN OR THIOPHENE DERIVATIVE AND MEDICINAL USE THEREOF

The present invention provides a compound represented by the formula (I): [wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, p is 0, 1 or 2, and when p is 2, each R may be the same or different, R1 is a hydrogen atom or an optionally substituted hydrocarbon group, R2 is an optionally substituted aromatic group, Ring A is an optionally substituted monocyclic aromatic ring or optionally substituted bicyclic aromatic fused ring, X1 is an oxygen atom or a sulfur atom, X2 is a bond, an oxygen atom or -S(O)n- (wherein n is 0, 1 or 2), Y is a bond, an oxygen atom, -S(O)m-, -C(=O)-N(R3)- or -N(R3)-C(=O)- (R3 is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, and m is 0, 1 or 2), M1, M2 and M3 may be the same or different and are each independently a bond or an optionally substituted divalent aliphatic hydrocarbon group, and M4 is an optionally substituted divalent aliphatic hydrocarbon group] or a salt thereof, which is useful as a prophylactic and/or therapeutic agent for lipid metabolism abnormality, arteriosclerotic disease and sequelae thereof, diabetes mellitus and the like.

Research on antibacterial and antifungal agents. III. Synthesis and antimicrobial activity of 2-methyl-5-aryl-3-furoic acids and 2-methyl-3-imidazolylmethyl-5-aryl furans

-