111795-96-1Relevant articles and documents
NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS
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, (2018/03/25)
The invention relates to novel heterocyclic compounds of general formula (I), as well as their pharmaceutically acceptable salts, and their enantiomers. The invention also relates to the use thereof as a medicinal product, preferably in the prevention and/or treatment of inflammatory diseases with a neurogenic component or use thereof as a cosmetic. The compounds of the present invention act as antagonists of the CGRP-R receptor.
An improved synthesis of 3-methyl-5-hydroxy protected indoles
Marino,Hurt
, p. 839 - 848 (2007/10/02)
The synthesis of 3-methyl-5-alkoxy indoles 14 and 15 was accomplished through the use of DIBALH to effect the reductive- cyclization of an amino-nitrile intermediate. The mild conditions used to induce cyclization allowed for the use of a benzyl protectin
THE USE OF o-NITROARYLACETONITRILES AS CARBON ACID PARTICIPANTS IN THE MITSUNOBU REACTION
Macor, John E.,Wehner, Jennifer M.
, p. 7195 - 7198 (2007/10/02)
The use of o-nitroarylacetonitriles as carbon acids in the Mitsunobu reaction is discussed as a method of carbon-carbon bond formation.This reaction represents a rare example of a carbon acid participating in a Mitsunobu reaction.
