111808-94-7

Basic information

• Product Name: 5-(4-CHLOROPHENYL)-3-HYDROXYMETHYL-2-METHYLFURAN
• Synonyms: 5-(4-CHLOROPHENYL)-3-HYDROXYMETHYL-2-METHYLFURAN;(5-(4-Chlorophenyl)-2-Methylfuran-3-yl)Methanol
• CAS NO: 111808-94-7
• Molecular Formula: C₁₂H₁₁ClO₂
• Molecular Weight: 222.67
• Mol File: 111808-94-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-CHLOROPHENYL)-3-HYDROXYMETHYL-2-METHYLFURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-CHLOROPHENYL)-3-HYDROXYMETHYL-2-METHYLFURAN(111808-94-7)
• EPA Substance Registry System: 5-(4-CHLOROPHENYL)-3-HYDROXYMETHYL-2-METHYLFURAN(111808-94-7)

Safety Data

• Hazardous Substances Data: 111808-94-7(Hazardous Substances Data)

Usage

Chemical structure

Furan derivative with a chlorophenyl group and a hydroxymethyl group attached to the furan ring, with a methyl group at the 2-position

Pharmacological properties

Studied for potential anti-inflammatory and antimicrobial activities

Pharmacological properties

Anti-inflammatory
Antimicrobial

Industrial uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Safety considerations

Handle with care due to potential health and environmental hazards

Chemical compound

5-(4-Chlorophenyl)-3-hydroxymethyl-2-methylfuran

Main properties

Furan derivative
Chlorophenyl group attached
Hydroxymethyl group attached
Methyl group at the 2-position

Uses

Intermediate in the synthesis of pharmaceuticals
Intermediate in the synthesis of agrochemicals

Hazards

Health hazards
Environmental hazards

Caution

Handle with care

Upstream product

• 111787-84-9 ethyl 5-(4-chlorophenyl)-2-methylfuran-3-carboxylate 
• 111787-89-4 2-methyl-5-(4-chlorophenyl)-furan-3-carboxylic acid 
• 111787-82-7 2-[2-(4-chlorophenyl)-2-oxo-ethyl]-3-oxo-butyric acid ethyl ester 
• 536-38-9 4-chlorobenzoylmethyl bromide 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound represented by the following formula (I), which has a glucagon antagonistic action and is useful for the prophylaxis or treatment of diabetes and the like, a compound represented by wherein ring A is an optionally substituted benzene ring and the like; Y is a nitrogen atom and the like; X is -O- and the like; R4 is a hydrogen atom and the like; R5 and R6 are each independently a hydrogen atom and the like; R1 is an optionally substituted hydrocarbon group and the like; R2 is a hydrogen atom and the like; and R3 is -(CH2)3-COOH and the like, or a salt thereof.

FURAN OR THIOPHENE DERIVATIVE AND MEDICINAL USE THEREOF

The present invention provides a compound represented by the formula (I): [wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, p is 0, 1 or 2, and when p is 2, each R may be the same or different, R1 is a hydrogen atom or an optionally substituted hydrocarbon group, R2 is an optionally substituted aromatic group, Ring A is an optionally substituted monocyclic aromatic ring or optionally substituted bicyclic aromatic fused ring, X1 is an oxygen atom or a sulfur atom, X2 is a bond, an oxygen atom or -S(O)n- (wherein n is 0, 1 or 2), Y is a bond, an oxygen atom, -S(O)m-, -C(=O)-N(R3)- or -N(R3)-C(=O)- (R3 is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, and m is 0, 1 or 2), M1, M2 and M3 may be the same or different and are each independently a bond or an optionally substituted divalent aliphatic hydrocarbon group, and M4 is an optionally substituted divalent aliphatic hydrocarbon group] or a salt thereof, which is useful as a prophylactic and/or therapeutic agent for lipid metabolism abnormality, arteriosclerotic disease and sequelae thereof, diabetes mellitus and the like.