111821-49-9 Usage
Description
4-BORONO-D-PHENYLALANINE B10 ENRICHED is a white crystalline powder that serves as a melanin precursor analog. It is specifically designed to deliver 10B to melanoma tissue, making it a crucial component in the field of boron neutron capture therapy (BNCT) for cancer treatment.
Uses
Used in Cancer Therapy:
4-BORONO-D-PHENYLALANINE B10 ENRICHED is used as a targeted delivery agent for boron in the context of boron neutron capture therapy. The primary application reason is its ability to selectively accumulate in melanoma tissue, allowing for the effective treatment of melanoma cancer cells while minimizing damage to surrounding healthy cells.
Check Digit Verification of cas no
The CAS Registry Mumber 111821-49-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,8,2 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 111821-49:
(8*1)+(7*1)+(6*1)+(5*8)+(4*2)+(3*1)+(2*4)+(1*9)=89
89 % 10 = 9
So 111821-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H12BNO4/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15/h1-4,8,14-15H,5,11H2,(H,12,13)/t8-/m1/s1
111821-49-9Relevant articles and documents
A high-yield synthesis of 4-borono-DL-phenylalanine
Park, Ki Chul,Yoshino, Kazuo,Tomiyasu, Hiroshi
, p. 2041 - 2044 (1999)
A high-yield synthesis of 4-borono-DL-phenylalanine has been achieved by a route which features a highly diastereoselective formation of the Z-isomer of a boron-containing dehydroamino acid derivative.
