111934-15-7Relevant articles and documents
Asymmetric Hetero Diels-Alder Reactions in Aqueous Solution Using Amino Acid Esters as Chiral Auxiliaries
Waldmann, Herbert
, p. 231 - 238 (2007/10/02)
(R)- and (S)-amino acid methyl ester hydrochlorides form with formaldehyde in THF/water mixtures iminium ions, which react already at 0 deg C as electron-deficient dienophiles in hetero Diels-Alder reactions with cyclopentadiene, cyclohexadiene, and open-
Immonium Ion Based Synthetic Methodology: A Novel Method for the N-Methylation of Dipeptides and Amino Acid Derivatives via Retro Aza Diels-Alder Reactions
Grieco, Paul A.,Bahsas, Ali
, p. 5746 - 5749 (2007/10/02)
A novel method for the N-methylation of amino acid derivatives and dipeptides is detailed that features facile room-temperature retro Diels-Alder reactions of N-substituted 2-azanorbornenes with trapping of the incipient immonium ion with triethylsilane/trifluoroacetic acid.