111943-73-8Relevant articles and documents
Synthesis and derivatization of 4-arylsulfonylthiophene- and furan-2-sulfonamides
Hartman,Halczenko
, p. 127 - 134 (1990)
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4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors
Hartman,Halczenko,Smith,Sugrue,Mallorga,Michelson,Randall,Schwam,Sondey
, p. 3822 - 3831 (2007/10/02)
A series of 4-substituted thiophene- and furan-2-sulfonamides was prepared and was found to possess nanomolar-level potency for inhibition of human carbonic anhydrase II in vitro. Selected examples from this group were further evaluated for their potentia