111969-65-4Relevant articles and documents
CHIRAL SYNTHESIS OF 3--4-OXOAZETIDIN-2-YL ACETATE USING AN ASYMMETRIC 1,3-DIPOLAR CYCLOADDITION REACTION
Kametani, Tetsuji,Chu, Shih-Der,Honda, Toshio
, p. 1593 - 1598 (2007/10/02)
3--4-oxoazetidin-2-yl acetate (4; R = H), a key intermediate for the preparation of penem and carbapenem antibiotics was synthesized in an optically active form using a 1,3-dipolar cycloaddition reaction of a chiral nitrone (6) as a key step.