111971-35-8Relevant articles and documents
ANALOGS OF PYRIMIDINE NUCLEOSIDES. 20. AMINOMETHYLATION OF 5-FLUOROURACIL AND THYMINE
Zhuk, R. A.,Ludzisha, A. S.,Kostyanovskii, R. G.
, p. 74 - 77 (1987)
Reactions were studied of 5-fluorouracil and thymine with formaldehyde and secondary amines (piperidine, morpholine) and also of their 2,4-bis(trimethylsilyl) derivatives with N-methoxymethylmorpholine and bis(amino)methanes.The N-aminomethylation products are slightly stable and in aqueous solutions decompose readily to the starting components; their structure was confirmed by PMR spectra.