112097-30-0Relevant articles and documents
SYNTHESIS OF N-UNSUBSTITUTED α-ALKYLATED PYRROL-2-ACETONITRILES
Muchowski, Joseph M.,Scheller, Marcus E.
, p. 863 - 876 (2007/10/02)
Nucleophilic addition of alkyllithium compounds to in situ generated 6-dimethylamino-1-azafulvene produced the α-alkylated pyrrole Mannich bases (3).Reaction of the p-toluenesulfonic acid salt of such bases with excess sodium cyanide in wet acetonitrile, at reflux temperature, provided the corresponding α-alkylpyrrol-2-acetonitriles (5) via the putative 6-alkyl-1-azafulvenes.