112135-33-8

Basic information

• Product Name: (1-(2-hydroxy)-phenyl)-N,N,N',N'-tetramethyl phosphonic diamide
• Synonyms: (1-(2-hydroxy)-phenyl)-N,N,N',N'-tetramethyl phosphonic diamide
• CAS NO: 112135-33-8
• Molecular Weight: 228.231
• Mol File: 112135-33-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1-(2-hydroxy)-phenyl)-N,N,N',N'-tetramethyl phosphonic diamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1-(2-hydroxy)-phenyl)-N,N,N',N'-tetramethyl phosphonic diamide(112135-33-8)
• EPA Substance Registry System: (1-(2-hydroxy)-phenyl)-N,N,N',N'-tetramethyl phosphonic diamide(112135-33-8)

Safety Data

• Hazardous Substances Data: 112135-33-8(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 770-12-7 O-phenyl phosphorodichloridate 
• 7393-13-7 (1-phenyl)-N,N,N',N'-tetramethyldiamido phosphate 

Relevant articles and documents

Anionic fries' type reaction in aryl tetramethyldiamidophosphates

n-BuLi lithiates aryl tetramethyldiamidophosphates adjacent to the tetramethyldiamidophosphate group, which migrates to the adjacent position.

ORTHO-LITHIATION OF PHENOLS USING THE BIS(DIMETHYLAMINO)PHOSPHORYL GROUP AS A DIRECTING GROUP

Aryl tetramethylphosphorodiamidates were effectively lithiated with sec-BuLi at -105 deg C to give ortho-lithiated species which provide ortho-substituted phosphates by treatment with a variety of electrophiles.KEYWORDS lithiation; phenol; bis(dimethylamino)phosphoryl group; phosphate; aryl tetramethylphosphorodiamidate