112217-97-7Relevant articles and documents
Facile synthesis of 4-substituted 3,4-dihydrocoumarins via an organocatalytic double decarboxylation process
Peng, Shiyong,Wang, Lei,Guo, Haibing,Sun, Shaofa,Wang, Jian
supporting information; experimental part, p. 2537 - 2541 (2012/04/23)
3,4-Dihydrocoumarins, considered to be valuable building blocks, have attracted considerable attention due to their various biological activities. Herein, we have documented an efficient and convenient double decarboxylation process for the synthesis of 4-substituted 3,4-dihydrocoumarin in moderate to excellent yields under mild reaction conditions (up to 98%). The Royal Society of Chemistry 2012.
Nhc-catalyzed reactions of aryloxyacetaldehydes: A domino elimination/conjugate addition/acylation process for the synthesis of substituted coumarins
Phillips, Eric M.,Wadamoto, Manabu,Roth, Howard S.,Ott, Andrew W.,Scheidt, Karl A.
supporting information; experimental part, p. 105 - 108 (2009/06/28)
N-Heterocyclic carbenes (NHCs) catalyze a domino Michael addition/acylation reaction to form 3,4-dihydrocoumarins. The reaction proceeds through addition of the NHC to an aryloxyaldehyde followed by elimination of a phenoxide leaving group, generating an
A δ-LACTONE SYNTHESIS INVOLVING AN INTRAMOLECULAR 1,4-ADDITION OF α-IODOACETATES TO ENONES
Demir, Ayhan S.,Gross, Raymond S.,Dunlap, Norma K.,Bashir-Hashemi, A.,Watt, David S.
, p. 5567 - 5570 (2007/10/02)
A cyclization of δ-(iodoacetoxy)-α,β-unsaturated ketones using iodotrimethylsilane involved a selective 1,4-addition of the acetate subunit to the enone and furnished δ-lactones in good yield.
