112251-19-1

Basic information

• Product Name: 3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>pregna-3,5-diene-20-one
• Synonyms: 3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>pregna-3,5-diene-20-one
• CAS NO: 112251-19-1
• Molecular Weight: 530.526
• Mol File: 112251-19-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>pregna-3,5-diene-20-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>pregna-3,5-diene-20-one(112251-19-1)
• EPA Substance Registry System: 3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>pregna-3,5-diene-20-one(112251-19-1)

Safety Data

• Hazardous Substances Data: 112251-19-1(Hazardous Substances Data)

Upstream product

• 57-83-0 Progesterone 
• 434-64-0 perfluorotoluene 

Downstream Products

• 57-83-0 Progesterone 

Relevant articles and documents

The Selective Protection of the 3-Ketone Functions of Steroids as Heptafluoro-p-tolyl Enol Ethers

Conjugated and unconjugated 3-ketone functions in steroids react with octafluorotoluene at above 100 deg C in the presence of caesium fluoride to give heptafluoro-p-tolyl enol ethers.The related but unusually reactive Wieland-Miescher ketone (11) reacted at room temperature in the presence of tetra-n-butylammonium fluoride.Enones were regenerated from their derivatives by acidic hydrolysis.Hydrolysis of the derivative (10) of 4,5α-dihydroxytestosterone was slu but sodium methoxide regenerated the parent steroid.The methods have been applied in a synthesis of deuterium-labelled testosterone.