112257-22-4

Basic information

• Product Name: Tert-butyl2-(piperazin-1-yl)acetate
• Synonyms: Tert-butyl2-(piperazin-1-yl)acetate
• CAS NO: 112257-22-4
• Molecular Formula: C10H20N2O2
• Molecular Weight: 200.278
• Mol File: 112257-22-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 275.4±25.0 °C(Predicted)
• Appearance: /
• Density: 0.998±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.94±0.10(Predicted)
• CAS DataBase Reference: Tert-butyl2-(piperazin-1-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Tert-butyl2-(piperazin-1-yl)acetate(112257-22-4)
• EPA Substance Registry System: Tert-butyl2-(piperazin-1-yl)acetate(112257-22-4)

Safety Data

• Hazardous Substances Data: 112257-22-4(Hazardous Substances Data)

Usage

General Description

Tert-butyl2-(piperazin-1-yl)acetate is an organic compound with the molecular formula C12H24N2O2. It is a tert-butyl ester derivative of piperazine-1-acetic acid and is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. This chemical is a colorless liquid with a mild, sweet odor and is soluble in water and most organic solvents. It is known for its diverse applications in chemical research, drug development, and as a building block in organic synthesis. Tert-butyl2-(piperazin-1-yl)acetate is an important compound in the pharmaceutical industry and is used in the production of various drugs and biologically active compounds.

Upstream product

• 110-85-0 piperazine 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 107-59-5 tert-Butyl chloroacetate 

Downstream Products

• 1620517-04-5 2-(4-(5-oxo-5-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenylamino)pentyl)piperazin-1-yl)acetic acid 
• 1620517-37-4 2-(4-(5-oxo-5-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenylamino)pentyl)piperazin-1-yl)acetic acid 
• 1620172-28-2 C₉₁H₁₅₇N₁₅O₁₈ 

Relevant articles and documents

BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY

The present invention relates to compounds of formula (I) useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY

The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Dihydropyrimidine compounds and their use in medicine

The invention relates to dihydropyrimidine compounds and application thereof in medicines, particularly application in medicines for treating and preventing hepatitis B. Particularly, the invention relates to compounds disclosed as general formula (I) or (Ia), or enantiomers, diastereoisomers, tautomerides, hydrates, solvates or pharmaceutically acceptable salts thereof, wherein the variables are defined in the specification. The invention also relates to application of the compounds disclosed as general formula (I) or (Ia), or enantiomers, diastereoisomers, tautomerides, hydrates, solvates or pharmaceutically acceptable salts thereof, especially application in medicines for treating and preventing hepatitis B.