112303-67-0

Basic information

• Product Name: S-tert-butyl (3R)-3-hydroxy-3-phenylpropanethioate
• Synonyms: S-tert-butyl (3R)-3-hydroxy-3-phenylpropanethioate
• CAS NO: 112303-67-0
• Molecular Weight: 238.351
• Mol File: 112303-67-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: S-tert-butyl (3R)-3-hydroxy-3-phenylpropanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-tert-butyl (3R)-3-hydroxy-3-phenylpropanethioate(112303-67-0)
• EPA Substance Registry System: S-tert-butyl (3R)-3-hydroxy-3-phenylpropanethioate(112303-67-0)

Safety Data

• Hazardous Substances Data: 112303-67-0(Hazardous Substances Data)

Upstream product

• 56377-45-8 Chlorthioessigsaeure-S-tert-butylester 
• 53635-52-2 S-tert-butyl 2-bromoethanethioate 
• 100-52-7 benzaldehyde 
• 175227-31-3 (S)-3-((R)-1-Methyl-3-trimethylsilanyloxy-propoxy)-3-phenyl-thiopropionic acid S-tert-butyl ester 
• 175227-22-2 (S)-3-((R)-3-Hydroxy-1-methyl-propoxy)-3-phenyl-thiopropionic acid S-tert-butyl ester 
• 79464-76-9 (2S,4R)-4-methyl-2-phenyl-1,3-dioxane 
• 63584-47-4 (1-tert-butylsulfanyl-vinyloxy)trimethylsilane 
• 175227-32-4 (S)-3-((R)-1-Methyl-3-oxo-propoxy)-3-phenyl-thiopropionic acid S-tert-butyl ester 
• 163881-60-5 (2S,3S)-2-Chloro-3-hydroxy-3-phenyl-thiopropionic acid S-tert-butyl ester 
• 163881-61-6 (2S,3S)-2-Bromo-3-hydroxy-3-phenyl-thiopropionic acid S-tert-butyl ester 
• 63584-41-8 1-ethylthio-1-(trimethylsiloxy)ethene 
• 999-90-6 S-tert-butyl thioacetate 

Relevant articles and documents

Catalytic, enantioselective hetero-Diels-Alder reaction with novel, chiral bis-titanium(IV) catalyst

Our recently designed chiral bis-titanium(IV) catalyst can be successfully utilized for the catalytic enantioselective hetero-Diels-Alder reaction of aldehyde and Danishefsky's diene. The high asymmetric induction is achievable in the case of sterically l

Asymmetric Synthesis of Functionalized Secondary Alcohols by Catalytic Ring-Cleavage Reactions of Cyclic Acetals Derived from (R)-1,3-Butanediol

In the presence of a catalytic amount (0.1-0.2 molar amount) of a 2-phenyl-1,3,2-oxazaborolidin-5-one, prepared by the reaction of dichlorophenylborane and N-(trifluoromethylsulfonyl)-L- phenylalanine, and enol silyl ethers ((R2)2C=C-(R3)OTMS; R3 = t-BuS, EtS, EtO, Ph) (1.1-1.5 molar amount), chiral cyclic acetals 6 derived from (R)-1,3-butanediol and aldehydes undergo an efficient ring-cleavage reaction with the inversion of the stereochemistry at the acetal carbon to give the anti isomer of the corresponding products with high stereoselectivity. The reaction is applicable to acetals derived from aromatic, aliphatic, and α,β-unsaturated aldehydes. Not only enol silyl ethers, but also methallyltrimethylsilane and allyltributyltin, can be employed as nucleophiles, leading to the selective formation of the anti isomer of the corresponding allylated ring-cleavage products. Removal of the chiral auxiliary from these ring-cleavage products by a two-step sequence ((i) PCC (ii) Bn2NH2(CF3CO2)) furnishes enantiomerically enriched β-hydroxy carbonyl compounds and homoallyl alcohols. A modest level of kinetic resolution is observed in the ring cleavage of a racemic acetal catalyzed by a phenylboron compound derived from N-mesyl-L-phenylalanine.

Computerunterstuetztes Design von chiralen Borenolaten: eine neue, hoch enantioselektive Aldolreaktion fuer Thioacetate und Thiopropionate

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