112459-79-7

Basic information

• Product Name: N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE
• Synonyms: N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE ;(4S)-3-(1-Oxobutyl)-4-(phenylMethyl)-2-oxazolidinone;(4S)-4-Benzyl-3-butyryl-1,3-oxazolidin-2-one;(S)-4-Benzyl-3-butyryloxazolidin-2-one
• CAS NO: 112459-79-7
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247.28968
• Product Categories: Miscellaneous Reagents
• Mol File: 112459-79-7.mol
• Article Data: 39

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE(112459-79-7)
• EPA Substance Registry System: N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE(112459-79-7)

Safety Data

• Hazardous Substances Data: 112459-79-7(Hazardous Substances Data)

Usage

Description

N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE is a cell-permeable N-(butyryl)oxazolidinone compound that is characterized by its oil-like chemical properties. It is primarily used as a negative control for the Cell Sheet Migration Inhibitor, which is a substance that inhibits the migration of cells in various biological processes.

Uses

Used in Biomedical Research:
N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE is used as a negative control for the Cell Sheet Migration Inhibitor in biomedical research. It serves as a reference point to compare the effects of other compounds on cell migration, allowing researchers to better understand the mechanisms and factors involved in this process.
Used in Pharmaceutical Development:
In the pharmaceutical industry, N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE may be used as a starting point for the development of new drugs targeting cell migration-related diseases. Its properties as a negative control can help researchers identify potential therapeutic agents that can modulate cell migration effectively.
Used in Drug Delivery Systems:
Similar to gallotannin, N-BUTYRYL-4-(S)-PHENYLMETHYL-2-OXAZOLIDINONE could potentially be incorporated into drug delivery systems to improve the bioavailability and therapeutic outcomes of various pharmaceutical agents. Its oil-like chemical properties may facilitate its incorporation into different types of carriers, such as organic and metallic nanoparticles.

Upstream product

• 90719-30-5 (4S)-3-((E)-2-butenoyl)-4-benzyl-2-oxazolidinone 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 141-75-3 butyryl chloride 
• 62763-37-5 butyric O-ethyl-carbonic anhydride 
• 101711-90-4 (S)-4-benzyl-2-oxazolidinone lithium salt 
• 107-92-6 butyric acid 
• 2314-97-8 iodotrifluoromethane 
• 106-31-0 butanoic acid anhydride 
• 143097-09-0 (R)-4-benzyl-3-(trimethylsilyl)-2-oxazolidinone 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 5267-64-1 (R)-2-amino-3-phenylpropanol 
• 673-06-3 D-(R)-phenylalanine 

Downstream Products

• 150615-45-5 (+)-(4S)-3-<(2'R)-2'-(hydroxymethyl)butanoyl>-4-benzyl-2-oxazolidinone 
• 130710-56-4 (S)-3-<(R)-2-ethyl-1-oxo-4-penten-1-yl>-4-(phenylmethyl)-1,3-oxazolidin-2-one 
• 130710-56-4 -4-benzyl-3-(2-ethyl-1-oxopent-4-enyl)oxazolidin-2-one 
• 156546-60-0 (S)-4-Benzyl-3-((S)-2-phenylsulfanyl-butyryl)-oxazolidin-2-one 
• 112530-24-2 (4S)-3-((2'R)-2'-methylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 112530-23-1 (4S)-3-((2'S)-2'-methylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 163457-34-9 (+)-(4S)-3-<(2'R)-2'-((benzyloxy)methyl)butanoyl>-4-benzyl-2-oxazolidinone 
• 500220-39-3 (S)-4-Benzyl-3-[(E)-(2S,3R,5R,6R,7R,8S)-5-(tert-butyl-dimethyl-silanyloxy)-2-ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-dodec-10-enoyl]-oxazolidin-2-one 
• 189760-91-6 (4S)-3-[(2R)-4-cyano-2-ethyl-1-oxobutan-1-yl]-4-(phenylmethyl)-1,3-oxazolidin-2-one 
• 198641-77-9 (S)-2-(4-tert-Butyl-benzyl)-butan-1-ol 
• 198641-66-6 2-tert-Butyl-5-((S)-2-hydroxymethyl-butyl)-phenol 
• 209671-27-2 (4S)-3-((2'S,3'R)-2'-ethyl-3'-hydroxy-4'-methylpentanoyl)-4-phenylmethyl-2-oxazolidinone 
• 215177-83-6 (4S,2'S,3'R)-3-(2'-ethyl-3'-hydroxypentanoyl)-4-benzyl-2-oxazolidinone 
• 253143-30-5 (R)-4-benzyl-3-((S)-2-ethylpent-4-enoyl)oxazolidin-2-one 

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Pd(0)-systems modified with SPINOL-derived phosphoramidate ligands promote highly enantioselective aza-Heck cyclizations of alkenyl N-(tosyloxy)carbamates. The method provides versatile access to challenging N-heterocycles and represents the broadest scope enantioselective aza-Heck protocol developed to date.

Asymmetric total synthesis of four stereoisomers of the sex pheromone of the western corn rootworm

A convergent synthesis of four stereoisomers of the sex pheromone of the western corn rootworm (8-methyldecan-2-yl propionate, 1) from commercially available chiral starting materials is reported. The key step was Julia–Kocienski olefination between chiral BT-sulfone and chiral aldehyde. This synthetic route provided the four stereoisomers of 1 in 24–29% total yield via a six-step sequence. The simple scale-up strategy provides a new way to achieve the asymmetric synthesis of the sex pheromone.