112533-09-2

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester
• CAS NO: 112533-09-2
• Molecular Formula: C8H7F3O4S
• Molecular Weight: 256.202
• Mol File: 112533-09-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester(112533-09-2)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester(112533-09-2)

Safety Data

• Hazardous Substances Data: 112533-09-2(Hazardous Substances Data)

Upstream product

• 17763-70-1 methyl 2-(trifluoromethylsulfonyloxy)benzoate 
• 84761-77-3 2-formylphenyl triflate 
• 90-02-8 salicylaldehyde 

Downstream Products

• 166959-36-0 2-benzylphenyl trifluoromethanesulfonate 
• 87-41-2 2-benzofuran-1(3H)-one 
• 21464-39-1 2-(acetyloxymethyl)benzophenone 
• 167031-45-0 2-(bromomethyl)phenyl trifluoromethanesulfonate 
• 112533-10-5 2-(acetyloxymethyl)phenyl trifluoromethanesulfonate 

Relevant articles and documents

A Chan-Evans-Lam approach to trisubstituted vinyl ethers

Trisubstituted vinyl ethers were accessedviaChan-Evans-Lam coupling of vinyl trifluoroborates and primary aliphatic alcohols. This approach complements prior methods that required the use of neat liquid alcohol coupling partners. A palladium-catalyzed redox-relay Heck reaction was used to convert several vinyl ethers into aldehyde-functionalized 1,3-dihydroisobenzofurans.

Nickel-Catalyzed Cross-Electrophile Coupling between Benzyl Alcohols and Aryl Halides Assisted by Titanium Co-reductant

A nickel-catalyzed cross-electrophile coupling reaction between benzyl alcohols and aryl halides has been developed using a homolytic C-O bond cleavage protocol that has recently been established. The treatment of a benzyl alcohol and aryl halide with a nickel catalyst and low-valent titanium reagent generated from TiCl4(lutidine) (lutidine = 2,6-lutidine) and manganese powder afforded the cross-coupled product in high yield. A mechanistic study indicated the intermediacy of the benzyl radicals that originate from the benzyl alcohols.