112671-87-1

Basic information

• Product Name: 2-Furancarboxamide, N-(2-oxo-2-phenylethyl)-
• CAS NO: 112671-87-1
• Molecular Formula: C13H11NO3
• Molecular Weight: 229.235
• Mol File: 112671-87-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Furancarboxamide, N-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxamide, N-(2-oxo-2-phenylethyl)-(112671-87-1)
• EPA Substance Registry System: 2-Furancarboxamide, N-(2-oxo-2-phenylethyl)-(112671-87-1)

Safety Data

• Hazardous Substances Data: 112671-87-1(Hazardous Substances Data)

Upstream product

• 88-14-2 2-furanoic acid 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 527-69-5 2-furancarbonyl chloride 
• 5468-37-1 2-aminoacetophenone hydrochloride 

Downstream Products

• 91804-24-9 2-(furan-2-yl)-5-phenyloxazole 

Relevant articles and documents

Synthesis method of alpha-acylamino ketone compound

The invention discloses a synthesis method of an alpha-acylamino ketone compound, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: mixingan alkenyl azide compound 1, a carboxylic acid compound 2 and an organic solvent, and heating to react to obtain the alpha-acylamino ketone compound 3. Compared with the prior art, the method has thefollowing advantages: (1) the synthesis process is simple and efficient, no catalyst is needed in the whole process, and the alpha-acylamino ketone compound can be obtained with high yield by dissolving the alkenyl azide compound and the carboxylic acid compound in the solvent and stirring; (2) raw materials are cheap and easy to obtain, reaction conditions are mild, and operation is simple; (3) the substrate is wide in application range and can be used for modifying drug molecules; and (4) the atom economy is high, and the requirements of green chemistry are met.