112716-28-6

Basic information

• Product Name: methyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-galactopyranoside
• Synonyms: methyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-galactopyranoside
• CAS NO: 112716-28-6
• Molecular Weight: 474.486
• Mol File: 112716-28-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-galactopyranoside(112716-28-6)
• EPA Substance Registry System: methyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-galactopyranoside(112716-28-6)

Safety Data

• Hazardous Substances Data: 112716-28-6(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 57817-52-4 methyl 6-O-p-tolylsulfonyl-β-D-galactopyranoside 
• 98-59-9 p-toluenesulfonyl chloride 
• 106248-66-2 1,2,3,4-tetra-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranose  
• 121424-21-3 O¹,O²,O³,O⁴-tetraacetyl-O⁶-(toluene-4-sulfonyl)-α-D-galactopyranose 
• 1824-94-8 methyl beta-D-galactopyranoside 
• 13046-90-7 2,3,4-tri-O-acetyl-6-O-(p-tolylsulfonyl)-α-D-galactosyl bromide 
• 67-56-1 methanol 

Downstream Products

• 57817-52-4 methyl 6-O-p-tolylsulfonyl-β-D-galactopyranoside 
• 14122-18-0 3,6-anhydro-D-galactose 
• 75869-74-8 3,6-anhydro-D-lyxo-hexosulose 1,2-bis(phenylhydrazone) 
• 357953-00-5 methyl 2,3,4-tri-O-acetyl-6-thio-6-[2'-(methyl 2-phenylacetate)]-β-D-galactopyranoside 

Relevant articles and documents

'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase

Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of substra

Synthesis and biological evaluation of sialylmimetics as rotavirus inhibitors

Rotaviruses cause severe gastroenteritis in infants and are estimated to be responsible for over 600 000 deaths annually, primarily in developing countries. The development of potential inhibitors of this virus is therefore of great interest, particularly since the safety and efficacy of rotaviral vaccines has recently been questioned. This study describes the synthesis of a variety of compounds that can be considered as mimetics of N-acetylneuraminic acid thioglycosides and the subsequent in vitro biological evaluation of these sialylmimetics as inhibitors of rotaviral infection. Our results show that readily accessible carbohydrate-based compounds have the potential to act as inhibitors of rotaviral replication in vitro, presumably through inhibition of the rotaviral adhesion process.