112741-70-5 Usage
Description
Ethyl 2-((tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)aMino)acetate, also known as N-(tert-Butyloxycarbonyl)-N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]-glycine Ethyl Ester, is a complex organic compound with a colorless oil appearance. It is characterized by its unique chemical structure, which includes a tert-butoxycarbonyl group, a hydroxy-1,2-diphenylethyl group, and an amino group attached to a glycine ethyl ester. Ethyl 2-((tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)aMino)acetate is known for its role in the synthesis of biologically significant molecules.
Uses
Used in Pharmaceutical Industry:
Ethyl 2-((tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)aMino)acetate is used as a reactant for the preparation of α-helices of BCL-2 domains. BCL-2 is a family of proteins that play a crucial role in regulating apoptosis, or programmed cell death. By contributing to the synthesis of these protein domains, this compound aids in the development of potential therapeutic agents targeting various diseases, including cancer.
Used in Biochemical Research:
In the field of biochemical research, Ethyl 2-((tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)aMino)acetate is utilized for the preparation of collagen cross-linking agents such as (5S,5’S)-Dihydroxy Lysinonorleucine (D452900). Collagen is a vital structural protein found in the extracellular matrix of various tissues, and its cross-linking is essential for maintaining tissue integrity and function. Ethyl 2-((tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)aMino)acetate's role in synthesizing cross-linking agents contributes to the study and development of treatments for conditions related to collagen abnormalities, such as Ehlers-Danlos syndrome and osteogenesis imperfecta.
Used in Chemical Synthesis:
Ethyl 2-((tert-butoxycarbonyl)((1S,2R)-2-hydroxy-1,2-diphenylethyl)aMino)acetate is also employed as an intermediate in the synthesis of various complex organic molecules and pharmaceutical compounds. Its unique structure allows for further chemical modifications and functionalization, making it a valuable building block in the development of novel drugs and bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 112741-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,7,4 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 112741-70:
(8*1)+(7*1)+(6*2)+(5*7)+(4*4)+(3*1)+(2*7)+(1*0)=95
95 % 10 = 5
So 112741-70-5 is a valid CAS Registry Number.
112741-70-5Relevant articles and documents
Chiral morphine quinoline compound preparation method and chiral amino acid preparation method of compound
-
, (2017/12/13)
The invention provides chiral morpholine compounds. The structural general formula of the chiral morpholine compounds is as shown in the description. The invention further comprises a preparation method of the chiral morpholine compounds. The chiral morpholine compounds are prepared by using benzoin as a starting material, performing reductive amination, and performing chemical resolution on enantiomers and acid-catalyzed ester condensation reaction. The invention further provides amino acid compounds prepared from the chiral morpholine compounds, and a preparation method and application of the amino acid compounds.
Asymmetric synthesis of N-tert-butoxycarbonyl α- Amino acids. synthesis of (5S,6R)-4-tert-butoxycarbonyl-5,6-diphenylmorpholin-2-ONE [(4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2S,3R)-)]
Williams, Robert M.,Sinclair, Peter J.,DeMong, Duane E.,Chen, Daimo,Zhai, Dongguan
, p. 18 - 30 (2017/09/19)
-
