112898-00-7 Usage
Description
FMOC-D-GLN-OH, also known as N2-Fmoc-D-glutamine, is an N-Fmoc-protected form of D-Glutamine, an unnatural isomer of L-Glutamine. It is found in human plasma and serves as a source of liberated ammonia. D-Glutamine can be synthesized enzymatically or obtained from cheeses, wine, and vinegars. It is characterized by its white crystalline appearance.
Uses
Used in Pharmaceutical Industry:
FMOC-D-GLN-OH is used as a pharmaceutical compound for the development of drugs targeting various medical conditions. Its role in determining the activity of Glutamine synthetase, an enzyme found in mammalian liver and brain, makes it a valuable compound for research and drug development.
Used in Enzyme Activity Determination:
FMOC-D-GLN-OH is used as a substrate for determining the activity of Glutamine synthetase, an enzyme that controls the use of nitrogen in cells. This application is crucial in understanding the enzyme's function and its role in cellular processes.
Used in Research and Development:
FMOC-D-GLN-OH is used as a research compound in the field of biochemistry and molecular biology. Its unique properties and interactions with other molecules make it a valuable tool for studying various biological processes and developing new therapeutic strategies.
Used in Food Industry:
FMOC-D-GLN-OH can be found in cheeses, wine, and vinegars, where it contributes to the taste and quality of these products. Its presence in these food items also indicates its potential use in the development of new food products and additives.
Check Digit Verification of cas no
The CAS Registry Mumber 112898-00-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,8,9 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 112898-00:
(8*1)+(7*1)+(6*2)+(5*8)+(4*9)+(3*8)+(2*0)+(1*0)=127
127 % 10 = 7
So 112898-00-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H20N2O5/c21-18(23)10-9-17(19(24)25)22-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H2,21,23)(H,22,26)(H,24,25)/t17-/m1/s1
112898-00-7Relevant articles and documents
Novel chiral stationary phases based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin combining cinchona alkaloid moiety
Zhu, Lunan,Zhu, Junchen,Sun, Xiaotong,Wu, Yaling,Wang, Huiying,Cheng, Lingping,Shen, Jiawei,Ke, Yanxiong
, p. 1080 - 1090 (2020/05/25)
Novel chiral selectors based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin connecting quinine (QN) or quinidine (QD) moiety were synthesized and immobilized on silica gel. Their chromatographic performances were investigated by comparing to the 3,5-dimethyl phenylcarbamoylated β-cyclodextrin (β-CD) chiral stationary phase (CSP) and 9-O-(tert-butylcarbamoyl)-QN-based CSP (QN-AX). Fmoc-protected amino acids, chiral drug cloprostenol (which has been successfully employed in veterinary medicine), and neutral chiral analytes were evaluated on CSPs, and the results showed that the novel CSPs characterized as both enantioseparation capabilities of CD-based CSP and QN/QD-based CSPs have broader application range than β-CD-based CSP or QN/QD-based CSPs. It was found that QN/QD moieties play a dominant role in the overall enantioseparation process of Fmoc-amino acids accompanied by the synergistic effect of β-CD moiety, which lead to the different enantioseparation of β-CD-QN-based CSP and β-CD-QD-based CSP. Furthermore, new CSPs retain extraordinary enantioseparation of cyclodextrin-based CSP for some neutral analytes on normal phase and even exhibit better enantioseparation than the corresponding β-CD-based CSP for certain samples.
