112947-93-0

Basic information

• Product Name: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE
• Synonyms: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE;2-(1H-benzo[d]imidazol-1-yl)ethanamine;2-(1H-1H-benzo[d]iMidazol-1-yl)ethanaMine
• CAS NO: 112947-93-0
• Molecular Formula: C₉H₁₁N₃*2ClH
• Molecular Weight: 161.2
• Mol File: 112947-93-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 280 °C
• Appearance: /
• CAS DataBase Reference: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE(112947-93-0)
• EPA Substance Registry System: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE(112947-93-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 112947-93-0(Hazardous Substances Data)

Usage

Description

2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE is a chemical compound that features a benzoimidazole ring connected to an ethylamine group. This small molecule possesses potential biological and pharmacological properties attributed to its unique structure. It is recognized for its utility in medicinal chemistry research, where it aids in the development of innovative drugs and pharmaceuticals. Additionally, it holds promise in organic synthesis and chemical biology, serving as a building block or intermediate for crafting more intricate molecules. In essence, 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE is a multifaceted chemical with a spectrum of potential applications across scientific and industrial fields.

Uses

Used in Medicinal Chemistry Research:
2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE is utilized as a key component in the development of novel drugs and pharmaceuticals, capitalizing on its distinctive structural attributes to enhance therapeutic efficacy and target specific biological pathways.
Used in Organic Synthesis:
In the realm of organic synthesis, 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE is employed as a valuable building block. It contributes to the construction of more complex organic molecules, facilitating advancements in chemical compound design and functionality.
Used in Chemical Biology:
2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE also serves as an intermediate in chemical biology, where it is instrumental in the preparation of intricate molecules for biological studies and potential applications in biomedicine.

Upstream product

• 86419-71-8 N-(2-nitrophenyl)ethylenediamine hydrochloride 

Downstream Products

• 905969-63-3 2-[(2-(1H-benzo[d]-imidazol-2-yl)ethylimino)methyl]phenol 
• 1442462-79-4 2-(2-(1H-benzimidazol-2-yl-ethylimino)methyl)-4-methylphenol 

Relevant articles and documents

Arylalkylamine-, β-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: Search for new lead structures

Specific serotonin receptor agonists and antagonists are marketed with respect to various diseases, most prominently severe emesis. To identify new chemical classes with affinity for the serotonin 5-HT3 channel, several compounds were synthesized which can be structurally classified as arylalkylamines, azecines, quinolizines and β-carbolines. These were tested in three models: 1. direct effect on ileum (overall model for contracting or relaxant effect), 2. antiserotoninergic effects on rat ileum (crude serotonin model), 3. inhibitory effect on the 5-HT3 receptor channel complex expressed in N1E-115 cells (serotonin-induced [14C]guanidinium influx (specific model)). Key findings and conclusion: Several azecine-type compounds exhibit 5-HT3 receptor channel antagonistic properties at concentrations close to that of tropisetron (used as a positive control) and might serve as potential lead structures for the development of further 5-HT3 channel receptor antagonists. ECV · Editio Cantor Verlag.