112995-51-4

Basic information

• Product Name: Ethanone, 2-(5-bromo-4-nitro-1H-imidazol-1-yl)-1-phenyl-
• CAS NO: 112995-51-4
• Molecular Formula: C11H8BrN3O3
• Molecular Weight: 310.107
• Mol File: 112995-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-(5-bromo-4-nitro-1H-imidazol-1-yl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-(5-bromo-4-nitro-1H-imidazol-1-yl)-1-phenyl-(112995-51-4)
• EPA Substance Registry System: Ethanone, 2-(5-bromo-4-nitro-1H-imidazol-1-yl)-1-phenyl-(112995-51-4)

Safety Data

• Hazardous Substances Data: 112995-51-4(Hazardous Substances Data)

Upstream product

• 532-27-4 1-chloroacetophenone 
• 6963-65-1 5-bromo-4-nitro-1H-imidazole 

Downstream Products

• 112995-66-1 5-ethylithio-4-nitro-1-phenacylimidazole 
• 112995-68-3 5-(2-aminophenylthio)-4-nitro-1-phenacylimidazole 
• 112995-67-2 5-benzylithio-4-nitro-1-phenacylimidazole 
• 112995-69-4 ethyl 3-hydroxy-7-nitro-3-phenyl-imidazo<5,1-b>thiazine-2-carboxylate 

Relevant articles and documents

Azoles. Part 4. Nucleophilic Substitution Reactions of Halogenoimidazoles

A number of N-protected derivatives of 2,4,5-tribromoimidazole, 4(5)-bromo-5(4)-nitroimidazole, and 2,4(5)-dibromo-5(4)-nitroimidazole have been prepared by standard procedures and treated with various nucleophiles.Whereas 2,4,5-tribromo (and tri-iodo)imidazole reacted with sodium benzenethiolate to give the corresponding 4,5-dihalogenoimidazole and diphenyl disulphide, 1-protected derivatives of 2,4,5-tribromoimidazole reacted with various sodium alkane (or arene)thiolates and with sodium isopropoxide, in isoprpopyl alcohol, by displacement of the 2-bromine atom. 1-Benzyl-5-bromo-4-nitroimidazole (14), 2-(5-bromo-4-nitroimidazol-1-yl)acetate (25), and 5-bromo-4-nitro-1-phenacylimidazole (26) reacted by displacement of the 5-bromine atom.The product arising from reaction of the last compound with ethyl 2-mercaptoacetate in ethanol in the presence of base, cyclised to give ethyl 3-hydroxy-7-nitro-3-phenylimidazolothiazine-2-carboxylate (35).