113003-48-8Relevant articles and documents
Synthesis and antifungal activity of novel aza-D-homosteroids, hydroisoquinolines, pyridines and dihydropyridines
Patrick,Kinsman
, p. 615 - 624 (2007/10/03)
A series of novel aza-D-homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of Candida strains and also Aspergillus species. A number of 4-substituted pyridines and tetrahydropyridines
Intramolecular Alkylations of Aromatic Compounds, XVIII: Synthesis of 3,4-Dihydro-1'-methylspiro
Reimann, Eberhard,Speckbacher, Johann,Lotter, Hermann
, p. 385 - 393 (2007/10/02)
Refluxing the tetrahydroyridines 10 in hydrobromic acid gives the title compounds 12 stereoselectively.Their structures and configurations were confirmed by NMR spectroscopy and X-ray analysis.The tetrahydropyridines 10 were prepared from the pyridinecarbonitriles 5 and Grignard reagents 6 by standard methods.