1132667-77-6

Basic information

• Product Name: dimethyl 3-phenyl-1-tosylaziridine-2,2-dicarboxylate
• Synonyms: dimethyl 3-phenyl-1-tosylaziridine-2,2-dicarboxylate
• CAS NO: 1132667-77-6
• Molecular Weight: 389.429
• Mol File: 1132667-77-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: dimethyl 3-phenyl-1-tosylaziridine-2,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 3-phenyl-1-tosylaziridine-2,2-dicarboxylate(1132667-77-6)
• EPA Substance Registry System: dimethyl 3-phenyl-1-tosylaziridine-2,2-dicarboxylate(1132667-77-6)

Safety Data

• Hazardous Substances Data: 1132667-77-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 868-26-8 dimethyl 2-bromomalonate 
• 108-59-8 malonic acid dimethyl ester 

Relevant articles and documents

Synthesis of Diversely Substituted Imidazolidines via [3+2] Cycloaddition of 1,3,5-Triazinanes with Donor-Acceptor Aziridines and Their Anti-Tumor Activity

A Y(OTf)3-catalyzed [3+2] cycloaddition of 1,3,5-triazinanes with donor-acceptor aziridines has been developed, accessing diversely substituted imidazolidines high efficiency. Mechanistic investigations support the formation of imidazolidines through an SN1-like pathway. Furthermore, these imidazolidines exhibit promising anti-tumor activity against a series of human cancer cell lines. (Figure presented.).

Stereoselective Lewis acid mediated (3+2) cycloadditions of N-H- and N-sulfonylaziridines with heterocumulenes

Alkyl and aryl isothiocyanates and carbodiimides are effective substrates in (3+2) cycloadditions with N-sulfonyl-2-substituted aziridines and 2-phenylaziridine for the synthesis of iminothiazolidines and iminoimidazolidines. Additionally, the stereoselec

Facile iodine(III)-induced oxidative cycloaddition of N-sulfonyl imines with methylene compounds under neutral conditions

An efficient oxidative cycloaddition of N-sulfonyl imines with methylene compounds using PhIO with a catalytic amount of KI under neutral conditions, which affords 2,2-difunctionalized aziridines in good to excellent yields, is reported.