113282-18-1Relevant articles and documents
Intramolecular trapping of an intermediate in the reduction of imines by a hydroxycyclopentadienyl ruthenium hydride: Support for a concerted outer sphere mechanism
Casey, Charles P.,Clark, Timothy B.,Guzei, Ilia A.
, p. 11821 - 11827 (2008/03/27)
Reduction of imines by [2,5-Ph2-3,4-Tol2(η 5-C4COH)]Ru(CO)2H (1) produces kinetically stable ruthenium amine complexes. Reduction of an imine possessing an intramolecular amine was studied to distinguish between inner sphere and outer sphere mechanisms. 1,4-Bn15NH(c-C6H10)=NBn (12) was reduced by 1 in toluene-d8 to give 85% of [2,5-Ph 2-3,4-Tol2(η4-C4CO)](CO) 2RuNHBn(c-C6H10)15NHBn (16-RuN, 15N), resulting from coordination of the newly formed amine to the ruthenium center, and 15% of trapping product [2,5-Ph2-3,4-Tol 2(η4-C4CO)](CO)2Ru 15NHBn(c-C6H10)NHBn (16-Ru15N,N), resulting from coordination of the intramolecular trapping amine. These results provide support for an outer sphere transfer of hydrogen to the imine to generate a coordinatively unsaturated intermediate, which can be trapped by the intramolecular amine. An opposing mechanism, requiring coordination of the imine nitrogen to ruthenium prior to hydrogen transfer, cannot readily explain the observation of the trapping product 16-Ru15N,N.
SYNTHESIS, NMR INVESTIGATION AND FAB-MS CHARACTERIZATION OF 1-AMINO-2-ARYLMETHYL-DIPHOSPHONATE ESTERS
Failla, Salvatore,Finocchiaro, Paolo,Hagele, Gerhard,Rapisardi, Roberto
, p. 79 - 90 (2007/10/02)
Variously substituted amino aryl-methyl-diphosphonate ethyl esters have been prepared in good yields by adding diethyl phosphonate to the corresponding Schiff bases.All compounds were characterized by NMR and MS-FAB techniques, which reveal the presence o
