1133-64-8

Basic information

• Product Name: (R,S)-N-NITROSOANABASINE
• Synonyms: (s)-3-(1-nitroso-2-piperidinyl)pyridine;1-nitroso-anabasin;1-nitrosoanabasine;n’-nitrosoanabasine;n-nitroso-2-(3’-pyridyl)piperidine;n-nitrosoanabasine;(s)-3-(1-Nitrosopiperidin-2-yl)-pyridine;3-[(2S)-1-Nitroso-2-piperidinyl]pyridine
• CAS NO: 1133-64-8
• Molecular Formula: C10H13N3O
• Molecular Weight: 191.22972
• EINECS: 200-659-6
• Product Categories: Nicotine Derivatives;Chiral Reagents;Heterocycles;Mutagenesis Research Chemicals
• Mol File: 1133-64-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 326.98°C (rough estimate)
• Flash Point: 9℃
• Appearance: /
• Density: 1.1311 (rough estimate)
• Vapor Pressure: 1.21E-05mmHg at 25°C
• Refractive Index: 1.4830 (estimate)
• Storage Temp.: ?20°C
• PKA: 5.49±0.12(Predicted)
• CAS DataBase Reference: (R,S)-N-NITROSOANABASINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R,S)-N-NITROSOANABASINE(1133-64-8)
• EPA Substance Registry System: (R,S)-N-NITROSOANABASINE(1133-64-8)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• Hazardous Substances Data: 1133-64-8(Hazardous Substances Data)

Usage

Description

(R,S)-N-NITROSOANABASINE, also known as the S-enantiomer metabolite of tobacco, is a specific N-nitrosamine with carcinogenic activity. It is characterized by its yellow low melting solid to yellow oil appearance. (R,S)-N-NITROSOANABASINE has been identified for its potential applications in various fields due to its unique chemical properties.

Uses

Used in Chemical Research:
(R,S)-N-NITROSOANABASINE is used as a research compound for studying the effects of N-nitrosamines on biological systems and their carcinogenic properties. The compound serves as a valuable tool in understanding the mechanisms behind cancer development and the role of tobacco-related chemicals in this process.
Used in Pharmaceutical Industry:
(R,S)-N-NITROSOANABASINE is used as a reference material for the development of new drugs and therapies targeting N-nitrosamine-related cancers. Its unique chemical properties make it a potential candidate for the creation of novel pharmaceutical agents that can counteract the harmful effects of N-nitrosamines.
Used in Environmental Monitoring:
(R,S)-N-NITROSOANABASINE is used as a marker compound in environmental monitoring and assessment of tobacco-related pollution. Its detection in various environmental samples can provide valuable information on the presence and distribution of carcinogenic N-nitrosamines, helping to identify potential health risks and guide mitigation strategies.
Used in Tobacco Industry:
(R,S)-N-NITROSOANABASINE is used as a reference compound in the tobacco industry for evaluating the safety and quality of tobacco products. By monitoring the levels of this specific N-nitrosamine, manufacturers can ensure that their products meet regulatory standards and minimize the health risks associated with tobacco consumption.

Safety Profile

Questionable carcinogen withexperimental carcinogenic data. When heated todecomposition it emits toxic fumes of NOx.

InChI:InChI=1/C10H13N3O/c14-12-13-7-2-1-5-10(13)9-4-3-6-11-8-9/h3-4,6,8,10H,1-2,5,7H2/t10-/m1/s1

Upstream product

• 494-52-0 Anabasine