113308-50-2Relevant articles and documents
NUCLEOPHILIC ADDITION TO 1,2,2,6,6-PENTAMETHYL-3,5-DIMETHYLENE-4-PIPERIDONE
Belostotskii, A. M.,Shapiro, A. B.
, p. 665 - 669 (2007/10/02)
Like branched primary amines, unbranched mercaptans react with 1,2,2,6,6-pentamethyl-3,5-dimethylene-4-piperidone to give products of ring opening.On the basis of the data obtained, a reaction scheme that includes the intermediate formation of 3,7-diazabicyclononan-9-one seems less likely as compared with a scheme involving elimination from the monocyclic piperidine system.It is also shown that steric interaction of the vicinal substituents is one of the important factors that promote β elimination.