113309-30-1

Basic information

• Product Name: 4-hydroxy-1-butanesulfonyl chloride
• Synonyms: 4-hydroxy-1-butanesulfonyl chloride
• CAS NO: 113309-30-1
• Molecular Weight: 172.633
• Mol File: 113309-30-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-1-butanesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-1-butanesulfonyl chloride(113309-30-1)
• EPA Substance Registry System: 4-hydroxy-1-butanesulfonyl chloride(113309-30-1)

Safety Data

• Hazardous Substances Data: 113309-30-1(Hazardous Substances Data)

Upstream product

• 14970-83-3 4-Mercapto-1-butanol 
• 113309-31-2 sodium 4-hydroxy-1-butanesulfinate 

Downstream Products

• 1633-83-6 1,4-butane sultone 

Relevant articles and documents

HYDROXYALKANESULFONYL CHLORIDES FROM CHLORINATION OF HYDROXYALKANESULFINATE SALTS IN A NONPOLAR MEDIUM: 3-HYDROXY-1-PROPANESULFONYL AND 4-HYDROXY-1-PROPANESULFONYL AND 4-HYDROXY-1-BUTANESULFONYL CHLORIDES

3-Hydroxy-1-propanesulfonyl chloride (1b) was obtained for the first time (admixed with 10percent of propane sultone, 2b) by chlorination of a dichloromethane suspension of sodium 3-hydroxy-1-propanesulfinate 93b). 4-Hydroxy-1-butanesulfonyl chloride (1c) containing 13percent butane sultone (2c) was prepared similarly from 3c.The cyclizations of 1b and 1c in CDCl3 containing 1-butanol (0.9 M) showed first order rate constants of 1.4 x 10-4 and 6.4 x 10-5 s-1, corresponding to effective concentrations of 4.5 x 102 and 2.1 x 102 M, respectively.Reaction of triethylamine in ethanol-d (a) with 1b gave exclusively the undeuterated sultone (2b), evidently by a direct cyclization, and (b) with 1c produced mainly ethyl 4-hydroxy-1-butanesulfonate largely monodeuterated at the α-position, and presumably formed by way of the sulfene (6c).