113311-35-6

Basic information

• Product Name: L-Tyrosine, O-[5-(2-amino-3-methoxy-3-oxopropyl)-2-hydroxyphenyl]-, methyl ester, (S)-
• CAS NO: 113311-35-6
• Molecular Formula: C20H24N2O6
• Molecular Weight: 388.42
• Mol File: 113311-35-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-Tyrosine, O-[5-(2-amino-3-methoxy-3-oxopropyl)-2-hydroxyphenyl]-, methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tyrosine, O-[5-(2-amino-3-methoxy-3-oxopropyl)-2-hydroxyphenyl]-, methyl ester, (S)-(113311-35-6)
• EPA Substance Registry System: L-Tyrosine, O-[5-(2-amino-3-methoxy-3-oxopropyl)-2-hydroxyphenyl]-, methyl ester, (S)-(113311-35-6)

Safety Data

• Hazardous Substances Data: 113311-35-6(Hazardous Substances Data)

Upstream product

• 20989-19-9 (2S)-2-amino-3-(4-methoxyphenyl)propan-1-ol 
• 126383-90-2 (S)-2-Benzyloxycarbonylamino-3-{3-[4-((S)-2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-phenoxy]-4-methoxy-phenyl}-propionic acid benzyl ester 
• 126383-89-9 ((S)-2-{3-[4-((S)-2-Benzyloxycarbonylamino-3-hydroxy-propyl)-phenoxy]-4-methoxy-phenyl}-1-hydroxymethyl-ethyl)-carbamic acid benzyl ester 
• 126383-88-8 C₃₃H₃₄N₂O₆ 
• 113311-30-1 (S)-2-Amino-3-{3-[4-((S)-2-amino-2-carboxy-ethyl)-phenoxy]-4-methoxy-phenyl}-propionic acid 
• 126383-87-7 N-[(S)-2-(3-Bromo-4-methoxy-phenyl)-1-hydroxymethyl-ethyl]-benzamide 
• 10418-01-6 N-benzoyl-L-tyrosine methyl ester 
• 126455-12-7 (S)-N-(1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)benzamide 
• 126383-86-6 (S)-2-Amino-3-(3-bromo-4-methoxy-phenyl)-propan-1-ol 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 160538-38-5 methyl (S)-2-(((benzyloxy)carbonyl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)propanoate 
• 60-18-4 L-tyrosine 
• 67470-21-7 3',5'-dibromo-L-tyrosine methyl ester 
• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 

Downstream Products

• 83118-65-4 Isodityrosine 

Relevant articles and documents

Oxidative phenol coupling - Tyrosine dimers and libraries containing tyrosyl peptide dimers

The principles of phenol oxidation are outlined and summarized. Various procedures were used to dimerize tyrosine derivatives, especially linear tripeptides and cyclohexapeptides, via cross-linking of their phenolic side-chains. The coupling was performed by potassium hexacyanoferrate(III), phenyliodine(III)-bis(trifluoroacetate), vanadium(V)-oxyfluoride or horseradish peroxidase. The individual dityrosine and isodityrosine derivatives obtained in preparative scale, as well as the peptide-dimer libraries generated, were characterized by HPLC and electrospray ionization mass spectrometry. Further analyses were carried out by NMR spectroscopy, fluorescence spectroscopy and gas chromatography.

FACILE CHEMICAL SYTHESIS OF S,S-ISODITYROSINE, A NATURALLY-OCCURRING CROSS-LINKING AMINO ACID

Ullmann coupling of the two protected S-tyrosine derivatives 6 and 9 afforded the protected isodityrosine 10 which was converted into the natural bis-amino acid S,S-isodityrosine 1 in good yield.