113317-61-6

Basic information

• Product Name: (+/-)-NIGULDIPINE HYDROCHLORIDE
• Synonyms: (+/-)-1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINE-DICARBOXYLIC ACID 3-(4,4-DIPHENYL-1-PIPERIDINYL)-PROPYL METHYL ESTER HYDROCHLORIDE;(+/-)-NIGULDIPINE HYDROCHLORIDE
• CAS NO: 113317-61-6
• Molecular Formula: C36H40ClN3O6
• Molecular Weight: 646.17
• Mol File: 113317-61-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+/-)-NIGULDIPINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-NIGULDIPINE HYDROCHLORIDE(113317-61-6)
• EPA Substance Registry System: (+/-)-NIGULDIPINE HYDROCHLORIDE(113317-61-6)

Safety Data

• Hazardous Substances Data: 113317-61-6(Hazardous Substances Data)

Usage

Description

(+/-)-NIGULDIPINE HYDROCHLORIDE is a pharmaceutical compound that functions as a selective α1-adrenoceptor antagonist and a new calcium antagonist. It is characterized by its ability to block specific receptors in the body, which can have various therapeutic applications.

Uses

Used in Pharmaceutical Industry:
(+/-)-NIGULDIPINE HYDROCHLORIDE is used as a therapeutic agent for the treatment of various medical conditions. Its selective action on α1-adrenoceptors and its calcium antagonist properties make it a valuable compound in the development of medications aimed at addressing specific health issues.
Used in Cardiovascular Applications:
In the cardiovascular field, (+/-)-NIGULDIPINE HYDROCHLORIDE is used as an antihypertensive agent to help lower blood pressure. Its calcium antagonist activity contributes to the relaxation of blood vessel walls, which in turn reduces the force of heart muscle contractions and subsequently lowers blood pressure.
Used in Urological Applications:
(+/-)-NIGULDIPINE HYDROCHLORIDE is also used in the treatment of benign prostatic hyperplasia (BPH). Its α1-adrenoceptor antagonist activity helps to relax the smooth muscles in the prostate and bladder neck, improving urine flow and reducing symptoms associated with BPH.
Used in Research and Development:
In addition to its clinical applications, (+/-)-NIGULDIPINE HYDROCHLORIDE is utilized in research settings to study the effects of α1-adrenoceptor and calcium channel modulation on various physiological processes. This helps in the development of new drugs and therapies for a range of conditions.