113342-33-9 Usage
Description
3-(2,4-DIMETHYLPHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID is an organic compound with the molecular formula C12H11N2O2. It features a pyrazole core with a carboxylic acid group at the 5-position and a 2,4-dimethylphenyl group at the 3-position. 3-(2,4-DIMETHYLPHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID is known for its potential applications in various fields, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
3-(2,4-DIMETHYLPHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID is used as a key intermediate compound for the synthesis of inhibitors targeting human carbonic anhydrases IX and XII. These enzymes are often overexpressed in various types of cancer cells, making them attractive therapeutic targets for cancer treatment. By inhibiting these enzymes, the compound can potentially disrupt the tumor's acidic microenvironment, which is crucial for cancer cell survival and metastasis.
Additionally, 3-(2,4-DIMETHYLPHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID may also be utilized in other applications within the pharmaceutical industry, such as the development of new drugs for other diseases or as a building block for the synthesis of other bioactive molecules. However, further research and development are required to explore these potential applications fully.
Check Digit Verification of cas no
The CAS Registry Mumber 113342-33-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,3,4 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 113342-33:
(8*1)+(7*1)+(6*3)+(5*3)+(4*4)+(3*2)+(2*3)+(1*3)=79
79 % 10 = 9
So 113342-33-9 is a valid CAS Registry Number.
113342-33-9Relevant articles and documents
HETEROCYCLIC COMPOUND AND p27Kip1 DEGRADATION INHIBITOR
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Paragraph 0352; 0353; 0354; 0355; 360, (2013/04/10)
A novel heterocyclic compound or a salt thereof useful for selectively inhibiting the degradation of p27Kip1 is provided. The compound or the salt thereof is represented by the following formula (1): wherein A represents an alkyl group, a cycloalkyl group, an aryl group or a heterocyclic group, the group A may have a substituent; the ring B represents a 5- to 8-membered monocyclic heterocyclic ring or a condensed ring containing the monocyclic heterocyclic ring, the ring B may have a substituent; the ring C represents an aromatic ring, the ring C may have a substituent; L represents a linker comprising a main chain having 3 to 5 atoms selected from the group consisting of a carbon atom, a nitrogen atom, an oxygen atom and a sulfur atom, wherein at least one atom in the main chain is a hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, the linker L may have a substituent; and n is 0 or 1.
