113447-72-6

Basic information

• Product Name: 8-hydroxyquinoline-7-carboxaldehyde benzoylhydrazone
• CAS NO: 113447-72-6
• Molecular Weight: 291.309
• Mol File: 113447-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-hydroxyquinoline-7-carboxaldehyde benzoylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 8-hydroxyquinoline-7-carboxaldehyde benzoylhydrazone(113447-72-6)
• EPA Substance Registry System: 8-hydroxyquinoline-7-carboxaldehyde benzoylhydrazone(113447-72-6)

Safety Data

• Hazardous Substances Data: 113447-72-6(Hazardous Substances Data)

Upstream product

• 613-94-5 benzoic acid hydrazide 
• 5683-78-3 8-hydroxy-7-quinolinecarboxaldehyde 

Relevant articles and documents

Antioxidation and DNA-binding properties of binuclear lanthanide(III) complexes with a schiff base ligand derived from 8-hydroxyquinoline-7- carboxaldehyde and benzoylhydrazine

8-Hydroxyquinoline-7-carboxaldehyde (8-HQ-7-CA), Schiff-base ligand 8-hydroxyquinoline-7-carboxaldehyde benzoylhydrazone, and binuclear complexes [LnL(NO3)(H2O)2]2 were prepared from the ligand and equivalent molar amounts of Ln(NO3)·6 H 2O (Ln=La3+, Nd3+, Sm3+, Eu 3+, Gd3+, Dy3+, Ho3+, Er 3+, Yb3+, resp.). Ligand acts as dibasic tetradentates, binding to LnIII through the phenolate O-atom, N-atom of quinolinato unit, and C=N and -O-C=N- groups of the benzoylhydrazine side chain. Dimerization of this monomeric unit occurs through the phenolate O-atoms leading to a central four-membered (LnO)2 ring. Ligand and all of the LnIII complexes can strongly bind to CT-DNA through intercalation with the binding constants at 105-106 m-1. Moreover, ligand and all of the LnIII complexes have strong abilities of scavenging effects for hydroxyl (HO.) radicals. Both the antioxidation and DNA-binding properties of LnIII complexes are much better than that of ligand. Copyright