113473-12-4

Basic information

• Product Name: methyl (3R,4R,5R)-3,4-dihydroxy-5-<(p-tolylsulfonyl)oxy>-1-cyclohexene-1-carboxylate
• Synonyms: methyl (3R,4R,5R)-3,4-dihydroxy-5-<(p-tolylsulfonyl)oxy>-1-cyclohexene-1-carboxylate
• CAS NO: 113473-12-4
• Molecular Weight: 342.37
• Mol File: 113473-12-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (3R,4R,5R)-3,4-dihydroxy-5-<(p-tolylsulfonyl)oxy>-1-cyclohexene-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (3R,4R,5R)-3,4-dihydroxy-5-<(p-tolylsulfonyl)oxy>-1-cyclohexene-1-carboxylate(113473-12-4)
• EPA Substance Registry System: methyl (3R,4R,5R)-3,4-dihydroxy-5-<(p-tolylsulfonyl)oxy>-1-cyclohexene-1-carboxylate(113473-12-4)

Safety Data

• Hazardous Substances Data: 113473-12-4(Hazardous Substances Data)

Upstream product

• 10226-78-5 methyl DL-(1,3,4/2,5)-2,3,4,5-tetra-O-acetyl-2,3,4,5-tetrahydroxycyclohexane-1-carboxylate 
• 104731-69-3 methyl DL-(1,3,4/2,5)-2,3,4,5-tetrahydroxycyclohexane-1-carboxylate 
• 104731-68-2 methyl DL-(1,3/2)-2,3-di-O-acetyl-2,3-dihydroxy-4-cyclohexene-1-carboxylate 
• 113409-78-2 (3aS,4S,5R,7R,7aR)-2,2-Dimethyl-4,7-bis-(toluene-4-sulfonyloxy)-hexahydro-benzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 113473-07-7 (1R,2S,3R,4S,5R)-2,3,4,5-Tetraacetoxy-cyclohexanecarboxylic acid methyl ester 
• 108867-04-5 (1R)-(+)-(1,3/2)-2,3-diacetoxy-4-cyclohexene-1-carboxylate 
• 113473-09-9 (3aR,4S,5R,7R,7aS)-4,7-Dihydroxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 113473-08-8 (1R,2S,3R,4S,5R)-2,3,4,5-Tetrahydroxy-cyclohexanecarboxylic acid methyl ester 
• 187227-25-4 (3aR,5S,7R,7aR)-5-Hydroxy-2,2-dimethyl-7-(toluene-4-sulfonyloxy)-hexahydro-benzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 97373-88-1 methyl (1R,3R,4S,5R)-1,5-dihydroxy-3,4-(isopropylidenedioxy)cyclohexane-1-carboxylate 
• 113473-11-3 methyl 3 L-(3,4/5)-3,4,5-trihydroxy-3,4-O-isopropylidene-5-O-p-tolylsulfonyl-1-cyclohexene-1-carboxylate 

Downstream Products

• 40983-58-2 methyl shikimate 
• 187227-22-1 (1S,5S,6S)-5-Azido-7-trityl-7-aza-bicyclo[4.1.0]hept-2-ene-3-carboxylic acid methyl ester 
• 187226-91-1 (3R,4S,5R)-5-Azido-4-methanesulfonyloxy-3-methoxymethoxy-cyclohex-1-enecarboxylic acid methyl ester 
• 187226-97-7 (3R,4R,5S)-4-Acetylamino-5-azido-3-methoxymethoxy-cyclohex-1-enecarboxylic acid methyl ester 
• 187226-68-2 (3R,4R,5S)-4-Acetylamino-5-azido-3-propoxy-cyclohex-1-enecarboxylic acid methyl ester 
• 208720-84-7 (3R,4R,5S)-4-Acetylamino-5-amino-3-methoxymethoxy-cyclohex-1-enecarboxylic acid methyl ester 
• 187226-95-5 (3R,4R,5S)-4-Amino-5-azido-3-methoxymethoxy-cyclohex-1-enecarboxylic acid methyl ester 
• 187226-89-7 (3R,4S,5R)-5-Azido-4-hydroxy-3-methoxymethoxy-cyclohex-1-enecarboxylic acid methyl ester 
• 187226-99-9 (3R,4R,5S)-4-Acetylamino-5-amino-3-methoxymethoxy-cyclohex-1-enecarboxylic acid 
• 208720-77-8 (3R,4R,5S)-4-Amino-5-azido-3-propoxy-cyclohex-1-enecarboxylic acid methyl ester 

Relevant articles and documents

Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: Design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

The design, synthesis, and in vitro evaluation of the novel carbocycles as transition-state-based inhibitors of influenza neuraminidase (NA) are described. The double bond position in the carbocyclic analogues plays an important role in NA inhibition as d