113493-41-7

Basic information

• Product Name: 2-Pyridinemethanol, a-(1-phenylethyl)-
• CAS NO: 113493-41-7
• Molecular Formula: C14H15NO
• Molecular Weight: 213.279
• Mol File: 113493-41-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Pyridinemethanol, a-(1-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinemethanol, a-(1-phenylethyl)-(113493-41-7)
• EPA Substance Registry System: 2-Pyridinemethanol, a-(1-phenylethyl)-(113493-41-7)

Safety Data

• Hazardous Substances Data: 113493-41-7(Hazardous Substances Data)

Upstream product

• 5029-67-4 2-iodopyridine 
• 94191-42-1 2-phenyl-1-(pyridin-2-yl)propan-1-one 
• 492-37-5 hydratropic acid 
• 103-82-2 phenylacetic acid 
• 109-09-1 2-chloropyridine 
• 34713-70-7 2-Phenylpropanal 
• 21970-13-8 (pyridin-2-yl)magnesium bromide 
• 110-86-1 pyridine 

Relevant articles and documents

Oxidative magnesiation of halogenopyridines: Introduction of electrophilic substituents to the pyridine moiety under the Barbier condition

Oxidative magnesiation of halogenopyridines was carried out using active magnesium prepared by the reduction of magnesium chloride, to give pyridinylmagnesium halides, which were treated with electrophiles to afford the corresponding pyridine derivatives.

Preparation of nitrogen-containing π-deficient heteroaromatic Grignard reagents: Oxidative magnesiation of nitrogen-containing π-deficient halogenoheteroaromatics using active magnesium

The oxidative magnesiation of nitrogen-containing π-deficient halogenoheteroaromatics using active magnesium was accomplished. Both magnesiation followed by addition of a carbonyl compound (Grignard reaction) and magnesiation in the presence of a carbonyl compound (Barbier reaction) were carried out to afford the corresponding product. Especially, the latter method enabled fused halogenodiazines such as 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine or 2-chloroquinoxaline to magnesiate at a mild temperature (-20 to 30 °C).