113513-61-4Relevant articles and documents
Synthesis and characterization of novel sulfonamides derivatives and their antimicrobial, antioxidant and cytotoxicity evaluation
Rehman, Hajira,Qadir, Abdul,Ali, Zulfiqar,Nazir, Shahid,Zahra, Asmat,Shahzady, Tanzeela Gulab
, p. 491 - 498 (2017)
Five novel sulfonamides derivatives HR5-HR8 and HR14 were synthesized by sulfonylation of primary or secondary amine in the presence of base through nucleophilic substitution reaction. Structural elucidation was carried out through FT-IR, UV, 1
Design, synthesis and biological evaluation of N-phenylsulfonylnicotinamide derivatives as novel antitumor inhibitors
Zhang, Hui,Lu, Xiang,Zhang, Li-Rong,Liu, Jia-Jia,Yang, Xian-Hui,Wang, Xiao-Ming,Zhu, Hai-Liang
experimental part, p. 1411 - 1416 (2012/04/23)
A series of novel N-phenylsulfonylnicotinamide derivatives (1-24) have been synthesized and evaluated as potential EGFR tyrosine kinase (TK) inhibitors. Among all the compounds, compound 10 (5-bromo-N-(4-chlorophenylsulfonyl) nicotinamide) showed the most
