113519-34-9

Basic information

• Product Name: 2-Cyclohexen-1-one, 3-[[2-(methoxymethyl)-1-pyrrolidinyl]amino]-5,5-dimethyl-, (S)-
• CAS NO: 113519-34-9
• Molecular Formula: C14H24N2O2
• Molecular Weight: 252.357
• Mol File: 113519-34-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexen-1-one, 3-[[2-(methoxymethyl)-1-pyrrolidinyl]amino]-5,5-dimethyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 3-[[2-(methoxymethyl)-1-pyrrolidinyl]amino]-5,5-dimethyl-, (S)-(113519-34-9)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 3-[[2-(methoxymethyl)-1-pyrrolidinyl]amino]-5,5-dimethyl-, (S)-(113519-34-9)

Safety Data

• Hazardous Substances Data: 113519-34-9(Hazardous Substances Data)

Upstream product

• 72748-99-3 (R)-1-Amino-2-(methoxymethyl)pyrrolidine 
• 126-81-8 dimedone 

Downstream Products

• 113519-45-2 (3R,4S)-1-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-7,7-dimethyl-2,5-dioxo-4-phenyl-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carboxylic acid methyl ester 
• 113519-52-1 (S)-7,7-Dimethyl-4-phenyl-4,6,7,8-tetrahydro-1H,3H-quinoline-2,5-dione 
• 113519-37-2 2-{(S)-[2-((S)-2-Methoxymethyl-pyrrolidin-1-ylamino)-4,4-dimethyl-6-oxo-cyclohex-1-enyl]-phenyl-methyl}-malonic acid dimethyl ester 

Relevant articles and documents

ASYMMETRIC MICHAEL ADDITION/LACTAMIZATION VIA SAMP-/RAMP-HYDRAZONES ENANTIOSELECTIVE SYNTHESIS OF SUBSTITUTED TETRAHYDRO-2,5(1H,3H)-QUINOLINEDIONES

An efficient and highly diastereo- and enantioselective annulation of cyclic 1.3-diketones to tetrahydro-quinolinediones of type 4 and 5 in good overall yields is described.The key step is the Michael addition of the corresponding lithiated SAMP-/RAMP-hydrazones to arylidenemalonates followed by lactamization with virtually complete asymmetric induction (de,ee98percent).