1135292-86-2 Usage
Description
1-(2-propoxyphenyl)-1-ethanamine hydrochloride, commonly known as propoxyphene, is a synthetic opioid analgesic and a chiral compound. It is recognized for its potent pain-relieving properties, comparable to those of codeine, and was traditionally used to manage moderate to severe pain. Propoxyphene operates by binding to the opioid receptors in the brain and spinal cord, which results in a diminished perception of pain. Despite its efficacy, concerns over its potential for addiction and serious cardiac side effects have led to its withdrawal from the market in several countries, including the United States and the United Kingdom.
Uses
Used in Pharmaceutical Industry:
1-(2-propoxyphenyl)-1-ethanamine hydrochloride was used as an analgesic agent for the treatment of moderate to severe pain. Its application was based on its ability to bind to opioid receptors in the brain and spinal cord, thereby reducing the perception of pain.
Used in Combination Therapy:
Propoxyphene was also utilized as a component in combination therapies, where it was often paired with non-opioid pain relievers such as acetaminophen. This combination aimed to enhance the overall analgesic effects and provide more effective pain management.
However, it is important to note that due to the potential risks associated with propoxyphene, including addiction and cardiac side effects, its use has been discontinued in many regions. As a result, alternative pain management strategies and medications are now preferred in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 1135292-86-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,5,2,9 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1135292-86:
(9*1)+(8*1)+(7*3)+(6*5)+(5*2)+(4*9)+(3*2)+(2*8)+(1*6)=142
142 % 10 = 2
So 1135292-86-2 is a valid CAS Registry Number.
1135292-86-2Relevant articles and documents
Comparison of different reducing systems in the synthesis of functionally substituted benzylamines from alkyl aryl ketones and aromatic aldehydes
Musatov,Starodubtseva,Turova,Kurilov,Vinogradov,Rakishev,Struchkova
experimental part, p. 1021 - 1028 (2010/11/03)
Different synthetic approaches to functionally substituted benzylamines were examined: reductive amination of alkyl aryl ketones and reduction of aromatic aldehyde oximes. The most efficient procedures were used to prepare a series of previously unknown h
