113544-39-1

Basic information

• Product Name: methyl 2-(2-fluoro-biphenyl-4-yl)propionate
• Synonyms: methyl 2-(2-fluoro-biphenyl-4-yl)propionate
• CAS NO: 113544-39-1
• Molecular Weight: 258.292
• Mol File: 113544-39-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-fluoro-biphenyl-4-yl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-fluoro-biphenyl-4-yl)propionate(113544-39-1)
• EPA Substance Registry System: methyl 2-(2-fluoro-biphenyl-4-yl)propionate(113544-39-1)

Safety Data

• Hazardous Substances Data: 113544-39-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 113544-32-4 (S)-3-O-(2-(2-fluoro-4-biphenyl)propionyl)-1,2-O-isopropylidene-α-D-glucofuranose 
• 5104-49-4 fluorobiprofen 
• 113544-32-4 (R)-3-O-(2-(2-fluoro-4-biphenyl)propionyl)-1,2-O-isopropylidene-α-D-glucofuranose 
• 1201594-47-9 C₁₂H₁₆FNO₅S 
• 98-80-6 phenylboronic acid 

Downstream Products

• 5104-49-4 (R)-flurbiprofen 
• 5104-49-4 fluorobiprofen 
• 1430219-38-7 2-{2'-fluoro-4'-[1-oxo-1-(6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino)propan-2-yl]biphenyl-4-yloxy}ethyl nitrate 
• 1430219-39-8 3-{2'-fluoro-4'-[1-oxo-1-(6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino)propan-2-yl]biphenyl-4-yloxy}propyl nitrate 
• 1430219-40-1 4-{2'-fluoro-4'-[1-oxo-1-(6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino)propan-2-yl]biphenyl-4-yloxy}butyl nitrate 
• 1430219-41-2 6-{2'-fluoro-4'-[1-oxo-1-(6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino)propan-2-yl]biphenyl-4-yloxy}hexyl nitrate 
• 1430219-42-3 2-{2'-fluoro-4'-[1-oxo-1-(8-(1,2,3,4-tetrahydroacridin-9-ylamino)octylamino)propan-2-yl]biphenyl-4-yloxy}ethyl nitrate 
• 1430219-43-4 3-{2'-fluoro-4'-[1-oxo-1-(8-(1,2,3,4-tetrahydroacridin-9-ylamino)octylamino)propan-2-yl]biphenyl-4-yloxy}propyl nitrate 
• 1430219-44-5 4-{2'-fluoro-4'-[1-oxo-1-(8-(1,2,3,4-tetrahydroacridin-9-ylamino)octylamino)propan-2-yl]biphenyl-4-yloxy}butyl nitrate 
• 1430219-45-6 6-{2'-fluoro-4'-[1-oxo-1-(8-(1,2,3,4-tetrahydroacridin-9-ylamino)octylamino)propan-2-yl]biphenyl-4-yloxy}hexyl nitrate 

Relevant articles and documents

Suzuki-Miyaura coupling of aryl carbamates, carbonates, and sulfamates

(Chemical Equation Presented) The first Suzuki-Miyaura cross-couplings of carbamates, carbonates, and sulfamates is described. The method provides a powerful means of using simple derivatives of phenol as precursors to polysubstituted aromatic compounds, as exemplified by a concise synthesis of the anti-inflammatory drug flurbiprofen.

ESTERS OF ARYLPROPIONIC ACIDS WITH 1,2:5,6-DI-O-ISOPROPYLIDENE- AND 1,2-O-ISOPROLYLIDENE-α-D-GLUCOFURANOSE

On fractional crystallization of 3-O-(2-(2-fluoro-4-biphenylyl)propionyl-, 3-O-(2-(4-isobutylphenyl)propionyl)- and 3-O-(2-(6-methoxy-2-naphthyl)propionyl)-1,2:5,6-di-O-isopropylidene-α-D-glucofuranoses V - VII optically pure R-diastereoisomers were isolated.The derivatives of 1,2-O-isopropylidene-α-D-glucofuranose obtained on partial deacetylation of esters V - VII were separated chromatographically to R and S-diastereoisomers.Their hydrolysis or transesterification afforded optically pure arylpropionic acids or their methyl esters, respectively.Kinetic resolutionof the acids gives rise to esters V - VII enriched in R-diastereoisomer.