113596-04-6

Basic information

• Product Name: 3'-AMINO-4'-FLUOROACETANILIDE
• Synonyms: N-(3-AMINO-4-FLUOROPHENYL)ACETAMIDE;3'-AMINO-4'-FLUOROACETANILIDE;3-AMINO-4-FLUOROACETANILIDE;AKOS BBV-007053;N-(3-amino-4-fluorophenyl)acetamide(SALTDATA: FREE);N-(3-Amino-4-fluorophenyl)acetamide, 5-(Acetylamino)-2-fluoroaniline;Acetamide, N-(3-amino-4-fluorophenyl)-
• CAS NO: 113596-04-6
• Molecular Formula: C₈H₉FN₂O
• Molecular Weight: 168.17
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 113596-04-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 165-167 °C(Solv: ethanol (64-17-5))
• Boiling Point: 365.6°C at 760 mmHg
• Flash Point: 174.9°C
• Appearance: /
• Density: 1.303g/cm³
• Vapor Pressure: 1.55E-05mmHg at 25°C
• Refractive Index: 1.61
• PKA: 13.80±0.70(Predicted)
• CAS DataBase Reference: 3'-AMINO-4'-FLUOROACETANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-AMINO-4'-FLUOROACETANILIDE(113596-04-6)
• EPA Substance Registry System: 3'-AMINO-4'-FLUOROACETANILIDE(113596-04-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 113596-04-6(Hazardous Substances Data)

Usage

General Description

3'-amino-4'-fluoroacetanilide is a chemical compound with the molecular formula C8H8FN2O. It is a derivative of acetanilide, which is a widely used analgesic and antipyretic drug. The presence of an amino group and a fluorine atom in the compound makes it useful for various organic synthesis processes. It is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. The chemical is a solid, white powder with a melting point of around 164-166°C. It is important to handle this compound with caution, as it may be harmful if ingested, inhaled, or comes into contact with the skin.

InChI:InChI=1/C8H9FN2O/c1-5(12)11-6-2-3-7(9)8(10)4-6/h2-4H,10H2,1H3,(H,11,12)

Upstream product

• 108-24-7 acetic anhydride 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 351-32-6 N-(4-fluoro-3-nitrophenyl)acetamide 

Relevant articles and documents

SULFIDE DYES

Formula (I) wherein R1 and R2 each independently from each other are a residue of an organic dye; Y1 and Y2 each independently from each other are unsubstituted or substituted, straightchain or branched, interrupted or uninterrupted -C1-C10alkylene-; -C5-C10cycloalkylene-; C5-C10arylene; or-C5-C10arylene-(C1-C10alkylene)-; Z1 and Z2 independently from each other are Formula (II) are each independently from each other hydrogen; or unsubstituted or substituted, straight-chain or branched, monocyclic or polycyclic, interrupted or uninterrupted C1-C14alkyl; C2-C14alkenyl; C6-C10aryl; C6-C10aryl-C1-C10alkyl; or C5-C10alkyl(C5-C10aryl); r, q and n independently from each other are 0 or 1, if n is 0, Z3 is hydrogen; and if n is 1, Z3 is -S-; with the proviso that the method does not comprise treating the fiber with an enzyme of the type of a protein disulfidisomerase (EC 5.3.4.1). Further, the present invention relates to novel disulfid compounds, compositions thereof, especially comprising other dyes, and to processes for their preparation.

One-pot reductive conversion of nitroarenes to N-arylacetamides mediated by metallic samarium

Nitroarenes can be reduced and then converted to N-arylacetamides by metallic samarium in the presence of acetic anhydride, acetic acid and methanol in excellent yields by a one pot-procedure.