113767-71-8

Basic information

• Product Name: Cyclohexanecarbonitrile, 2,6-dimethyl-1-[(trimethylsilyl)oxy]-
• CAS NO: 113767-71-8
• Molecular Formula: C12H23NOSi
• Molecular Weight: 225.406
• Mol File: 113767-71-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarbonitrile, 2,6-dimethyl-1-[(trimethylsilyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarbonitrile, 2,6-dimethyl-1-[(trimethylsilyl)oxy]-(113767-71-8)
• EPA Substance Registry System: Cyclohexanecarbonitrile, 2,6-dimethyl-1-[(trimethylsilyl)oxy]-(113767-71-8)

Safety Data

• Hazardous Substances Data: 113767-71-8(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 5337-72-4 2,6-dimethylcyclohexanol 
• 2816-57-1 2,6-dimethylcyclohexanone 

Downstream Products

• 52152-27-9 1-demethylretinal 
• 113767-73-0 (2E,4E)-5-(2,6-dimethyl-1-cyclohexenyl)-3-methyl-2,4-pentadienal 
• 102877-95-2 2,6-dimethyl-1-cyclohexenecarboxaldehyde 
• 113767-72-9 2,6-dimethyl-1-cyclohexenecarbonitrile 

Relevant articles and documents

Synthesis of cyanooxovanadate and cyanosilylation of ketones

The cyanosilylation was performed by using metavanadate catalysts, and in situ measurements revealed the formation of [VO2(CN)3]2- and [VO4TMS2]- under reaction conditions. The reaction of [VO2(CN)3]2-, trimethylsilyl cyanide (TMSCN), and water afforded [

Bacteriorhodopsin. The influence of the cyclohexene-ring methyls

Four ring-demethylated retinals, viz. 1,1',5-tridemethylretinal, 1,1'-didemethylretinal, 1,5-didemethylretinal and 1-demethylretinal, have been synthesized via new and simple schemes.The properties of these modified retinals, their protonated Schiff bases and the corresponding bacteriorhodopsins have been studied and compared with the native system.These bacteriorhodopsin analogues have also been tested for their proton-pump efficiencies.A large decrease in proton-pump activity was found for the analogues lacking the 5-methyl group.On the whole, the opsin shifts of the modified bacteriorhodopsins were much lower than those of the native system.UV-Vis and 1H NMR data support a planar 6-s-trans conformation for the demethylated retinals in solution rather than a twisted 6-s-cis conformation (torsion angle 40-60 deg) as found in retinal.This explains the lower opsin shift and the better fit of these demethylated retinals in bacteriorhodopsin's binding site, which, in its native form, contains a 6-s-trans chromophore.