113853-53-5Relevant articles and documents
Chemical modification of an antitumor alkaloid, 20(S)-camptothecin: Glycosides, phosphates and sulfates of 7-ethyl-10-hydroxycamptothecin
Yaegashi,Nokata,Sawada,Furuta,Yokokura,Miyasaka
, p. 131 - 135 (2007/10/02)
Water-soluble derivatives having the lactone ring intact were synthesized starting from 7-ethyl-10-hydroxycamptothecin (1). Glycosides (2) of the phenolic hydroxyl group of 1 were obtained by reaction with acetylated α-bromosugars in acetone or aqueous ac