1139879-57-4

Basic information

• Product Name: N-(5-iodopyrimidin-4-yl)-L-4-(N,N-dimethylcarbamyloxy)phenylalanine tert-butyl ester
• Synonyms: N-(5-iodopyrimidin-4-yl)-L-4-(N,N-dimethylcarbamyloxy)phenylalanine tert-butyl ester
• CAS NO: 1139879-57-4
• Molecular Weight: 512.347
• Mol File: 1139879-57-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(5-iodopyrimidin-4-yl)-L-4-(N,N-dimethylcarbamyloxy)phenylalanine tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-iodopyrimidin-4-yl)-L-4-(N,N-dimethylcarbamyloxy)phenylalanine tert-butyl ester(1139879-57-4)
• EPA Substance Registry System: N-(5-iodopyrimidin-4-yl)-L-4-(N,N-dimethylcarbamyloxy)phenylalanine tert-butyl ester(1139879-57-4)

Safety Data

• Hazardous Substances Data: 1139879-57-4(Hazardous Substances Data)

Upstream product

• 284486-57-3 L-4-(N,N-dimethylcarbamyloxy)phenylalanine tert-butyl ester 
• 63558-65-6 4-chloro-5-iodopyrimidine 

Downstream Products

• 285139-51-7 C₂₂H₂₂N₄O₄ 
• 1139879-62-1 C₂₆H₃₀N₄O₄ 
• 1273561-02-6 C₂₂H₂₀Cl₂N₄O₄ 
• 821800-31-1 N-(5-(2,6-difluorophenyl)pyrimidin-4-yl)-L-4-(N,N-dimethylcarbamyloxy)phenylalanine 
• 1273561-07-1 C₂₁H₂₁N₅O₄ 
• 821800-37-7 C₂₁H₂₁N₅O₄ 
• 285139-85-7 C₂₃H₂₄N₄O₅ 
• 285140-40-1 C₂₂H₂₁FN₄O₄ 
• 285139-55-1 C₂₃H₂₁F₃N₄O₄ 
• 285139-97-1 C₂₂H₂₁N₅O₆ 
• 285139-99-3 C₂₃H₂₄N₄O₄ 
• 285139-43-7 N-(5-(2,4,6-trimethylphenyl)pyrimidin-4-yl)-L-4-(N,N-dimethylcarbarnyloxy) phenylalanine 

Relevant articles and documents

Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma model

A series of N-(pyrimidin-4-yl)-phenylalanine VLA-4 antagonists is described. Optimization of substituents at the 2 and 5 positions of the pyrimidine ring gave 14, a very potent VLA-4 inhibitor which is orally active in a sheep asthma model.