1140512-58-8 Usage
Description
Methyl 6-Chloro-1H-Pyrrolo[2,3-b]Pyridine-2-Carboxylate is an organic compound with a chemical structure that features a pyrrolo[2,3-b]pyridine core, which is a fused ring system consisting of a pyrrole and a pyridine. The molecule is characterized by the presence of a chlorine atom at the 6th position and a carboxylate group at the 2nd position, which is esterified with a methyl group. Methyl 6-Chloro-1H-Pyrrolo[2,3-b]Pyridine-2-Carboxylate is of interest in the pharmaceutical industry due to its potential applications in the development of novel therapeutic agents.
Uses
Used in Pharmaceutical Industry:
Methyl 6-Chloro-1H-Pyrrolo[2,3-b]Pyridine-2-Carboxylate is used as a key intermediate in the synthesis of pharmaceutical 6,5 heterobicyclic ring derivatives. These derivatives are specifically designed to target and modulate the activity of the Stimulator of Interferon Genes (STING) protein, which plays a crucial role in the innate immune response. By targeting STING activation, these heterobicyclic ring derivatives have the potential to treat a range of inflammatory conditions, including autoimmune disorders and chronic inflammatory diseases.
The compound's unique chemical structure allows for the development of highly selective and potent STING modulators, which can either activate or inhibit the protein's function, depending on the specific therapeutic goal. In the context of inflammatory conditions driven by STING activation, Methyl 6-Chloro-1H-Pyrrolo[2,3-b]Pyridine-2-Carboxylate-based derivatives may serve as potential anti-inflammatory agents, offering a new approach to managing these disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1140512-58-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,0,5,1 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1140512-58:
(9*1)+(8*1)+(7*4)+(6*0)+(5*5)+(4*1)+(3*2)+(2*5)+(1*8)=98
98 % 10 = 8
So 1140512-58-8 is a valid CAS Registry Number.
InChI:InChI=1S/C9H7ClN2O2/c1-14-9(13)6-4-5-2-3-7(10)12-8(5)11-6/h2-4H,1H3,(H,11,12)
1140512-58-8Relevant articles and documents
As a receptor antagonist CRTH2 heterorings compd.
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Paragraph 0077, (2016/10/10)
This application relates to a compound of Formula ! (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an antagonist of receptor CRTH2, as well as a process for its preparation and interm
