114125-66-5Relevant articles and documents
CONDENSATION REACTIONS INVOLVING THE α-METHYLENE GROUP IN SERIES OF 5-ALKYLPYRROLIDINE-2-THIONES AND 5-ALKYL-1-ACETYL-2-PYRROLIDONES
Bespalova, G. V.,Sedavkina, V. I.,Kharchenko, V. G.,Shebaldova, A. D.,Labunskaya, V. L.
, p. 951 - 953 (1987)
It is shown that 1-substituted and N-substituted 5-R-pyrrolidine-2-thiones, in contrast to their oxygen analogs, undergo methylenethioalkylation and the Mannich and Michael reactions at the 3 position of the ring; this is due to their higher CH acidity.Th