1142811-44-6Relevant articles and documents
Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase
Donghi, Monica,Attenni, Barbara,Gardelli, Cristina,Marco, Annalise Di,Fiore, Fabrizio,Giuliano, Claudio,Laufer, Ralph,Leone, Joseph F.,Pucci, Vincenzo,Rowley, Michael,Narjes, Frank
scheme or table, p. 1392 - 1395 (2009/10/02)
A variety of new prodrugs of 2′-methyl cytidine based on acyloxy ethylamino phosphoramidates have been synthesized and tested in vitro and in vivo for their biological activity. Compared with the parent drug a 10- to 20-fold increase in formation of nucle