1142945-86-5

Basic information

• Product Name: 7H-Pyrrolo[2,3-d]pyriMidine, 2-chloro-7-[(4-Methylphenyl)sulfonyl]-4-(4-Methyl-2-thienyl)-
• Synonyms: 7H-Pyrrolo[2,3-d]pyriMidine, 2-chloro-7-[(4-Methylphenyl)sulfonyl]-4-(4-Methyl-2-thienyl)-;2-Chloro-4-(4-methylthiophen-2-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
• CAS NO: 1142945-86-5
• Molecular Formula: C₁₈H₁₄ClN₃O₂S₂
• Molecular Weight: 403.90566
• Mol File: 1142945-86-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7H-Pyrrolo[2,3-d]pyriMidine, 2-chloro-7-[(4-Methylphenyl)sulfonyl]-4-(4-Methyl-2-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-Pyrrolo[2,3-d]pyriMidine, 2-chloro-7-[(4-Methylphenyl)sulfonyl]-4-(4-Methyl-2-thienyl)-(1142945-86-5)
• EPA Substance Registry System: 7H-Pyrrolo[2,3-d]pyriMidine, 2-chloro-7-[(4-Methylphenyl)sulfonyl]-4-(4-Methyl-2-thienyl)-(1142945-86-5)

Safety Data

• Hazardous Substances Data: 1142945-86-5(Hazardous Substances Data)

Usage

General Description

The chemical "7H-Pyrrolo[2,3-d]pyriMidine, 2-chloro-7-[(4-Methylphenyl)sulfonyl]-4-(4-Methyl-2-thienyl)-" is a compound with a complex molecular structure. It consists of a pyrrolopyrimidine core with a 2-chloro substituent and a sulfonyl group attached to the 7th position. Additionally, it contains a 4-(4-methyl-2-thienyl) moiety and a 4-methylphenyl group. This chemical may have potential pharmaceutical or research applications due to its unique structure, but further investigation is necessary to fully understand its properties and potential uses.

Upstream product

• 934524-10-4 2,4-dichloro-7-p-methylbenzenesulfonyl-7H-pyrrole[2,3-d]pyrimidin-4-amine 
• 162607-15-0 (4-methyl-2-thienyl)boronic acid 

Downstream Products

• 1142947-84-9 C₃₀H₃₀N₆O₃S₂ 
• 1142946-05-1 N-[4-(1H-imidazol-1-yl)phenyl]-4-(4-methylthiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 1142948-10-4 C₂₇H₂₃N₅O₅S₂ 
• 1142946-03-9 4-(4-methylthiophen-2-yl)-N-[4-(2-morpholin-4-ylethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 1245648-55-8 C₂₉H₂₉N₅O₃S₂ 
• 1142947-38-3 [3-(4-methyl-piperazine-1-sulfonyl)-phenyl]-[4-(4-methyl-thiophen-2-yl)-7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-amine 
• 1142948-08-0 C₃₀H₃₁N₅O₃S₂ 
• 1142948-09-1 C₂₈H₂₄N₆O₂S₂ 
• 1142946-71-1 1-(4-(4-(4-(4-methylthiophen-2-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)benzyl)piperazin-1-yl)ethanone 

Relevant articles and documents

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.